Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 2/20 | 0.53 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CCND3 | P30281 | 1/20 | 0.37 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.37 |
| ▸ | CDK9 | P50750 | 2/20 | 0.37 |
| ▸ | DYRK2 | Q92630 | 2/20 | 0.37 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | NPY1R | P25929 | 1/20 | 0.36 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.36 |
| ▸ | NPY2R | P49146 | 1/20 | 0.36 |
| ▸ | AR | P10275 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30333809 | 0.85 | PCSK9 (0.57) | PCSK9DYRK1AKMT2AMEN1MAPT | |
| SCHEMBL31222719 | 0.83 | GPR84 (0.52) | PCSK9F7F3KMT2AMEN1 | |
| SCHEMBL30333581 | 0.78 | PCSK9 (0.60) | PCSK9DYRK1AKMT2AMEN1DYRK1B | |
| SCHEMBL31222717 | 0.69 | PCSK9 (0.57) | PCSK9KMT2AMEN1SMN1; SMN2CCND3 | |
| SCHEMBL11229272 | 0.68 | MAPT (0.47) | F7F3KMT2AMEN1MAPT | |
| SCHEMBL523253 | 0.68 | RHEB (0.54) | F7F3KMT2AMEN1MAPT | |
| SCHEMBL3762044 | 0.68 | KDM4E (0.50) | DYRK1ASMN1; SMN2CDK9DYRK2DYRK1B | |
| SCHEMBL29414225 | 0.67 | KMT2A (0.46) | F7F3KMT2AMEN1MAPT | |
| SCHEMBL3064168 | 0.67 | KMT2A (0.46) | F7F3KMT2AMEN1MAPT | |
| SCHEMBL27417845 | 0.67 | HRH4 (0.47) | F7F3KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240417399-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS AND THERAPEUTIC USES THEREOF | GALILEO BIOSYSTEMS INC (US) | 2024-12-19 | — | — | US | disclosed |
| WO-2023064486-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS AND THERAPEUTIC USES THEREOF | GALILEO BIOSYSTEMS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240417399-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS AND THERAPEUTIC USES THEREOF | AHR, ARNT, NR1H2 | PCSK9 1709/4885DYRK1A 3164/4885F7 4878/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.