Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.57 |
| ▸ | CCND3 | P30281 | 1/20 | 0.49 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.46 |
| ▸ | CDK9 | P50750 | 2/20 | 0.45 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.45 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | JAK2 | O60674 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.40 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30333331 | 0.85 | PCSK9 (0.53) | PCSK9CCND3CDK6NPC1RAB9A | |
| SCHEMBL30333581 | 0.82 | PCSK9 (0.60) | PCSK9PDE10ADYRK1ADYRK1BMEN1 | |
| SCHEMBL31222717 | 0.82 | PCSK9 (0.57) | PCSK9CCND3CDK6NPC1RAB9A | |
| SCHEMBL30333332 | 0.77 | MAP2K1 (0.51) | PCSK9CCND3CDK6NPC1RAB9A | |
| SCHEMBL27654304 | 0.76 | RAB9A (0.60) | PCSK9CCND3CDK6NPC1RAB9A | |
| SCHEMBL250171 | 0.73 | CCND3 (0.70) | CCND3CDK6NPC1RAB9ACDK9 | |
| SCHEMBL25668814 | 0.73 | CCND3 (0.58) | PCSK9CCND3CDK6NPC1RAB9A | |
| SCHEMBL3762044 | 0.72 | KDM4E (0.50) | CDK9DYRK1ADYRK2DYRK1BHTT | |
| Hydrochloric Acid SCHEMBL7000982 | 0.72 | CCND3 (0.68) | CCND3CDK6NPC1RAB9ACDK9 | |
| SCHEMBL31222719 | 0.71 | GPR84 (0.52) | PCSK9CCND3CDK6GPR84MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240417399-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS AND THERAPEUTIC USES THEREOF | GALILEO BIOSYSTEMS INC (US) | 2024-12-19 | — | — | US | disclosed |
| WO-2023064486-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS AND THERAPEUTIC USES THEREOF | GALILEO BIOSYSTEMS, INC. (US) | 2023-04-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240417399-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATORS AND THERAPEUTIC USES THEREOF | AHR, ARNT, NR1H2 | PCSK9 1709/4885CCND3 4004/4885CDK6 2833/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.