Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 19/20 | 0.45 |
| ▸ | MTOR | P42345 | 16/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 3/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 4/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.42 |
| ▸ | PRKDC | P78527 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | RICTOR | Q6R327 | 1/20 | 0.42 |
| ▸ | RPTOR | Q8N122 | 1/20 | 0.42 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.42 |
| ▸ | MAPKAP1 | Q9BPZ7 | 1/20 | 0.42 |
| ▸ | MLST8 | Q9BVC4 | 1/20 | 0.42 |
| ▸ | IRAK3 | Q9Y616 | 1/20 | 0.42 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15556197 | 0.85 | MTOR (0.55) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL462714 | 0.84 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL29610307 | 0.84 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30333881 | 0.84 | PIK3CA (0.59) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL791058 | 0.81 | GLO1 (0.47) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL17833788 | 0.81 | PIK3CA (0.53) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30902253 | 0.80 | PIK3CA (0.55) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL25390717 | 0.80 | PIK3CA (0.42) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30572690 | 0.80 | PIK3CA (0.42) | PIK3CAMTORPIK3R1PIK3CGPIK3CD | |
| SCHEMBL30333651 | 0.79 | CCKBR (0.47) | PIK3CAMTORPIK3R1PIK3CGPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |
| WO-2023045960-A1 | PYRIDINE DERIVATIVE AND USE THEREOF | 四川汇宇制药股份有限公司 | 2023-03-30 | — | — | WO | disclosed |