Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLO1 | Q04760 | 8/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.46 |
| ▸ | CGAS | Q8N884 | 1/20 | 0.45 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL358926 | 0.83 | PIK3CG (0.63) | SLC40A1PIK3CGPIK3CAMTORPIK3CD | |
| SCHEMBL30333387 | 0.81 | PIK3CA (0.45) | PIK3CGPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL789565 | 0.80 | PIK3CA (0.57) | GLO1SLC40A1BRAFPIK3CGCYP17A1 | |
| SCHEMBL28549695 | 0.80 | PIK3CG (0.50) | PIK3CGPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL30902213 | 0.79 | PIK3CA (0.56) | BRAFPIK3CGSLC22A12PIK3CAMTOR | |
| SCHEMBL15555632 | 0.79 | PIK3CA (0.56) | BRAFPIK3CGSLC22A12PIK3CAMTOR | |
| Ammonia Solution, Strong SCHEMBL28564473 | 0.79 | PIK3CG (0.49) | PIK3CGPIK3CAMTORPIK3CDPIK3CB | |
| SCHEMBL790895 | 0.78 | ALDH1A1 (0.61) | SLC40A1 | |
| SCHEMBL790434 | 0.78 | ALPL (0.54) | GLO1SLC40A1BRAFPIK3CGCYP17A1 | |
| SCHEMBL30333651 | 0.78 | CCKBR (0.47) | SLC40A1PIK3CGPIK3CAMTORPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |