Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | WNT1 | P04628 | 1/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 2/20 | 0.37 |
| ▸ | GRM1 | Q13255 | 2/20 | 0.37 |
| ▸ | PIM1 | P11309 | 1/20 | 0.37 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.37 |
| ▸ | LGMN | Q99538 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formic Acid SCHEMBL30423402 | 0.73 | KDM4E (0.42) | KDM4EMAOAMAOBNOTUMMAPK1 | |
| SCHEMBL892319 | 0.71 | SMN1; SMN2 (0.49) | KDM4EGSK3BSMN1; SMN2NPC1POLB | |
| SCHEMBL28201512 | 0.71 | MAOA (0.54) | KDM4EDYRK1AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL25222244 | 0.70 | BACE1 (0.43) | KDM4EWNT1DYRK1AGSK3BSMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL28856319 | 0.70 | MAOA (0.53) | KDM4EDYRK1AMAOAMAOBSMN1; SMN2 | |
| SCHEMBL31341117 | 0.70 | HSD17B1 (0.56) | KDM4EGSK3BSMN1; SMN2NPC1POLB | |
| SCHEMBL906668 | 0.69 | GRM5 (0.46) | GRM5GRM1 | |
| SCHEMBL31341150 | 0.68 | PTPN11 (0.58) | DYRK1AGSK3BSMN1; SMN2NPC1RAB9A | |
| SCHEMBL6604867 | 0.68 | SMN1; SMN2 (0.69) | KDM4EGSK3BSMN1; SMN2NPC1POLB | |
| SCHEMBL999672 | 0.68 | GSK3B (0.49) | KDM4EDYRK1AGSK3BSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4416156-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | Remix Therapeutics Inc. (US) | 2024-08-21 | — | — | EP | disclosed |
| WO-2023064879-A1 | COMPOUNDS AND METHODS FOR MODULATING NUCLEIC ACID SPLICING | REMIX THERAPEUTICS INC. (US) | 2023-04-20 | — | — | WO | disclosed |