Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.46 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | GSK3A | P49840 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
| ▸ | RNF4 | P78317 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345427 | 0.81 | NPC1 (0.59) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL9370053 | 0.75 | EPHX2 (0.71) | GLSALDH1A1GAAEPHX2LTA4H | |
| SCHEMBL9366598 | 0.75 | RAB9A (0.62) | GLSALDH1A1GAABRAFEPHX2 | |
| SCHEMBL8987764 | 0.75 | RIOK2 (0.51) | GLSRIOK2ALDH1A1GAAEPHX2 | |
| SCHEMBL28449008 | 0.74 | EGLN1 (0.48) | GLSGAAEPHX2LTA4H | |
| SCHEMBL30345516 | 0.74 | EGLN1 (0.48) | GLSGAAEPHX2LTA4H | |
| SCHEMBL16061776 | 0.73 | EPHX2 (0.50) | RIOK2ADORA3ADORA2AEPHX2GSK3A | |
| SCHEMBL28996113 | 0.72 | GLS (0.40) | GLSALDH1A1GAAP2RX7ADORA3 | |
| SCHEMBL13491705 | 0.72 | WNT3A (0.52) | GLSRIOK2ALDH1A1GAAP2RX7 | |
| SCHEMBL18657627 | 0.72 | RAB9A (0.74) | ALDH1A1GAAEPHX2RNF4NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | disclosed |