Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 9/20 | 0.48 |
| ▸ | THRA | P10827 | 9/20 | 0.43 |
| ▸ | THRB | P10828 | 9/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | ASPH | Q12797 | 1/20 | 0.42 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.42 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.42 |
| ▸ | GLS | O94925 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.41 |
| ▸ | LTA4H | P09960 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30345516 | 1.00 | EGLN1 (0.48) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL28897243 | 0.86 | EGLN1 (0.50) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL30345304 | 0.86 | EGLN1 (0.50) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL28442664 | 0.86 | EGLN1 (0.50) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL30345507 | 0.86 | EGLN1 (0.50) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL30345434 | 0.80 | EGLN1 (0.52) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL28449287 | 0.80 | EGLN1 (0.52) | EGLN1THRATHRBBBOX1SLC6A2 | |
| SCHEMBL28439104 | 0.78 | ITGB3 (0.53) | — | |
| SCHEMBL30345412 | 0.78 | ITGB3 (0.53) | — | |
| SCHEMBL30345520 | 0.74 | GLS (0.48) | GLSGAAEPHX2LTA4H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | claimed |
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | claimed |
| CN-111559982-B | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2023-04-07 | — | — | CN | disclosed |
| CN-111559982-A | 2- (2-substituted-4-hydroxypyrimidine-5-formamido) acetic acid compound and preparation method and application thereof | 天津市医药科学研究所 | 2020-08-21 | — | — | CN | disclosed |