SCHEMBL3034679

SCHEMBL3034679

CC(=O)N1CCC(C(=O)N(CCCN2CCC(Cc3ccc(C(N)=O)cc3)CC2)c2ccc(C)c(Cl)c2)CC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CCR5 P51681 19/20 1.00
KCNH2 Q12809 1/20 0.68

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29395387 1.00 CCR5 (1.00) CCR5KCNH2
SCHEMBL4771825 0.94 CCR5 (1.00) CCR5
SCHEMBL18038094 0.91 CCR5 (0.83) CCR5KCNH2
SCHEMBL12531217 0.90 CCR5 (0.86) CCR5KCNH2
SCHEMBL4773696 0.90 CCR5 (0.89) CCR5KCNH2
SCHEMBL12531274 0.90 CCR5 (0.89) CCR5KCNH2
SCHEMBL12531355 0.90 CCR5 (0.86) CCR5KCNH2
SCHEMBL4775460 0.90 CCR5 (0.86) CCR5KCNH2
SCHEMBL3034563 0.90 CCR5 (0.90) CCR5KCNH2
SCHEMBL30227460 0.90 CCR5 (0.90) CCR5KCNH2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108561-A1 COMPOSITION FOR CELL TRANSPLANTATION THERAPY AND THE USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2026-04-23 US claimed
US-12440571-B2 Immune agonists SHENZHEN UNIVERSITY (CN) 2025-10-14 US claimed
EP-4598598-A1 COMPOSITION FOR CELL TRANSPLANTATION THERAPY AND THE USE THEREOF National University of Singapore (SG) 2025-08-13 EP claimed
US-20250170172-A1 METHODS FOR TREATING LENTIVIRUS INFECTION JERICHO SCIENCES LLC (US) 2025-05-29 US claimed
WO-2024076303-A1 COMPOSITION FOR CELL TRANSPLANTATION THERAPY AND THE USE THEREOF NATIONAL UNIVERSITY OF SINGAPORE (SG) 2024-04-11 WO claimed
WO-2023164293-A1 METHODS FOR VIRAL INFECTIONS JERICHO SCIENCES, LLC (US) 2023-08-31 WO claimed
US-20230172912-A1 COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION HEIDELBERG IMMUNOTHERAPEUTICS GMBH (DE) 2023-06-08 US claimed
US-20230108709-A1 Immune Agonists SHENZHEN UNIVERSITY (CN) 2023-04-06 US claimed
EP-4132525-A1 COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION Heidelberg ImmunoTherapeutics GmbH (DE) 2023-02-15 EP claimed
CN-107614515-B T20 construct for anti-HIV (human immunodeficiency Virus) therapy and/or vaccine 免疫医疗公司 2022-03-22 CN claimed
EP-1498138-A1 PREVENTIVES FOR HIV INFECTION Takeda Pharmaceutical Company Limited (JP) 2005-01-19 EP claimed
US-20040053936-A1 Medicinal composition for oral use TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2004-03-18 US claimed
EP-1354587-A1 MEDICINAL COMPOSITIONS FOR ORAL USE Takeda Chemical Industries, Ltd. (JP) 2003-10-22 EP claimed
US-20030114443-A1 Cyclic amine compounds as CCR5 antagonists TOBIRA THERAPEUTICS, INC. 2003-06-19 US claimed
US-6562978-B1 N-(3-(4-(4-(Aminocarbonyl)benzyl)-1-piperidinyl)propyl)-N-(3, 4-dichlorophenyl)-1-(methylsulfonyl)-4-piperidinecarboxamide or a salt thereof for treatment of AIDS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2003-05-13 US claimed
EP-1220842-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS Takeda Chemical Industries, Ltd. (JP) 2002-07-10 EP claimed
EP-1147107-A4 NOVEL ANGIOGENESIS INHIBITORS MERCK & CO INC (US) 2002-05-22 EP claimed
EP-1147107-A1 NOVEL ANGIOGENESIS INHIBITORS Merck & Co., Inc. (US) 2001-10-24 EP claimed
WO-2001025200-A1 CYCLIC AMINE COMPOUNDS AS CCR5 ANTAGONISTS TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-04-12 WO claimed
WO-2000043393-A1 NOVEL ANGIOGENESIS INHIBITORS MERCK & CO., INC. (US) 2000-07-27 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250170172-A1 METHODS FOR TREATING LENTIVIRUS INFECTION ZC3HAV1, ZC3HAV1L, ZFR CCR5 54/4885KCNH2 4589/4885
US-20260108561-A1 COMPOSITION FOR CELL TRANSPLANTATION THERAPY AND THE USE THEREOF CCR5, CCRL2, CXCL12 CCR5 1/4885KCNH2 3233/4885
US-20230108709-A1 Immune Agonists TLR7, TLR3, TLR1 CCR5 221/4885KCNH2 3856/4885
US-12440571-B2 Immune agonists TLR7, TLR3, TLR1 CCR5 221/4885KCNH2 3856/4885
US-20030114443-A1 Cyclic amine compounds as CCR5 antagonists CCR5, CCR1, CCR3 CCR5 1/4885KCNH2 174/4885
US-20040053936-A1 Medicinal composition for oral use CCR5, CXCR3, CCL5 CCR5 1/4885KCNH2 3882/4885
US-20230172912-A1 COMPOUNDS FOR TREATING PNEUMONIA, SEPSIS, AND CORONAVIRUS INFECTION CCR5, CXCR3, CCL5 CCR5 1/4885KCNH2 1013/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.