L-Name

L-Name

SCHEMBL3034749

COC(=O)[C@@H](N)CCCNC(=N)N[N+](=O)[O-]

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NOS1 P29475 3/20 0.41
DPP7 Q9UHL4 2/20 0.35
NOS3 P29474 2/20 0.33
NOS2 P35228 1/20 0.33
ALDH1A1 P00352 1/20 0.33
NPY4R P50391 2/20 0.32
NPY1R P25929 1/20 0.32
OTC P00480 1/20 0.32
DPP8 Q6V1X1 1/20 0.32
DPP9 Q86TI2 1/20 0.32
GNAI3 P08754 1/20 0.31
GNAO1 P09471 1/20 0.31
GNAI1 P63096 1/20 0.31
TSHR P16473 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
L-Name SCHEMBL14751988 1.00 NOS1 (0.41) NOS1DPP7NOS3NOS2ALDH1A1
L-Name SCHEMBL18812631 0.99 NOS1 (0.40) NOS1DPP7NOS3NOS2ALDH1A1
L-Name SCHEMBL25310005 0.99 NOS1 (0.40) NOS1DPP7NOS3NOS2ALDH1A1
SCHEMBL836044 0.92 ALDH1A1 (0.34) NOS1ALDH1A1
SCHEMBL12556180 0.87 MEN1 (0.39) NOS1DPP7NOS3NOS2DPP8
Nitroarginine SCHEMBL28365071 0.84 NOS1 (0.48) NOS1NOS3NOS2OTC
SCHEMBL5983469 0.84 NOS1 (0.46) NOS1DPP7NOS3NOS2OTC
Nitroarginine SCHEMBL345312 0.84 NOS1 (0.48) NOS1NOS3NOS2OTC
Nitroarginine SCHEMBL881062 0.84 NOS1 (0.48) NOS1NOS3NOS2OTC
SCHEMBL607060 0.84 NOS1 (0.46) NOS1DPP7NOS3NOS2OTC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1099 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260102400-A1 PHARMACEUTICAL COMPOSITION FOR DISRUPTING TUMOR BLOOD VESSELS SAMSUNG MEDICAL FOUND (KR) 2026-04-16 US claimed
EP-4709378-A1 COMPOUNDS FOR NOS-RELATED CANCERS AND METHODS OF USE Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. (IL) 2026-03-18 EP claimed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
US-20250367371-A1 HYBRID BIOELECTRONIC/ENGINEERED CELL IMPLANTABLE SYSTEM FOR THERAPEUTIC AGENTS DELIVERY AND APPLICATIONS THEREOF UNIV NORTHWESTERN (US) 2025-12-04 US claimed
US-20250276085-A1 SYNTHETIC MULTIDOMAIN PEPTIDE BIOMATERIALS THAT INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE WILLIAM MARSH RICE UNIVERSITY (US) 2025-09-04 US claimed
EP-4591865-A1 PHARMACEUTICAL COMPOSITION FOR DISRUPTING TUMOR BLOOD VESSELS Samsung Medical Foundation (KR) 2025-07-30 EP claimed
WO-2025122600-A1 COMPOSITIONS AND METHODS FOR TREATING ABERRANT NITROSYLATION CASE WESTERN RESERVE UNIVERSITY (US) 2025-06-12 WO claimed
CN-120091822-A Pharmaceutical composition for tumor vascular blockage 三星医疗财团 2025-06-03 CN claimed
CN-119969334-A Method for constructing heart failure and pulmonary artery high pressure animal model 中国医学科学院基础医学研究所 2025-05-13 CN claimed
WO-2025091023-A1 ENGINEERED CELL TRANSFECTED BY ALL-IN-ONE VECTOR FOR THERAPEUTIC AGENTS PRODUCTION AND DELIVERY AND APPLICATIONS THEREOF NORTHWESTERN UNIVERSITY (US) 2025-05-01 WO claimed
WO-2022153308-A1 TOPICAL COMPOSITION RICH PSC LTD. (IL) 2022-07-21 WO claimed
EP-3967303-A1 INOS-INHIBITORY COMPOSITIONS AND THEIR USE AS BREAST CANCER THERAPEUTICS The Methodist Hospital (US) 2022-03-16 EP claimed
EP-3154585-B1 USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY GREEN KATHY A (US) 2022-02-23 EP claimed
WO-2022035049-A1 NOVEL METHOD FOR PREPARING ANIMAL MODEL OF CEREBROVASCULAR DISEASE AND METHOD FOR PRODUCING ANIMAL HAVING SMALL INDIVIDUAL DIFFERENCE IN SUSCEPTIBILITY TO CEREBROVASCULAR DISEASE ONSET BY USING ANIMAL MODEL FOR CEREBROVASCULAR DISEASE PREPARED THEREBY 동국대학교 산학협력단 2022-02-17 WO claimed
US-20220040298-A1 USE OF VISTA AGONISTS AND ANTAGONISTS TO SUPPRESS OR ENHANCE HUMORAL IMMUNITY DARTMOUTH COLLEGE (US) 2022-02-10 US claimed
EP-2256498-B1 Methods of diagnosing or treating irritable bowel syndrome and other disorders CEDARS SINAI MEDICAL CENTER (US) 2015-04-08 EP claimed
CN-101594885-A Rifaximin anti-rectal dysfunction preparation SALIX PHARMACEUTICALS INC (US) 2009-12-02 CN claimed
EP-1920776-A1 Prevention of damage in hippocampus of fetus/newborn infant due to maternal gestational hypertension Kindway International Ltd. (CN) 2008-05-14 EP claimed
US-20080038288-A1 Prevention of damage in hippocampus of fetus/newborn infant due to maternal gestational hypertension KINDWAY INTERNATIONA LIMITED (HK) 2008-02-14 US claimed
WO-2002080893-A1 TREATMENT OF LOW BACK PAIN AND WHIPLASH ASSOCIATED DISORDER A+ SCIENCE INVEST AB (SE) 2002-10-17 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260102400-A1 PHARMACEUTICAL COMPOSITION FOR DISRUPTING TUMOR BLOOD VESSELS RNMT, PNP, NOS1 NOS1 3/4885DPP7 2682/4885NOS3 4/4885
US-20250276085-A1 SYNTHETIC MULTIDOMAIN PEPTIDE BIOMATERIALS THAT INHIBIT INDUCIBLE NITRIC OXIDE SYNTHASE STING1, CGAS, GMPS NOS1 4/4885DPP7 1058/4885NOS3 17/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.