Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.47 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | SMO | Q99835 | 1/20 | 0.46 |
| ▸ | UBE2T | Q9NPD8 | 1/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2706925 | 0.91 | PARP1 (0.53) | HPGDSKCNH2HDAC2HDAC3OPRM1 | |
| SCHEMBL29524173 | 0.91 | PARP1 (0.53) | HPGDSKCNH2HDAC2HDAC3OPRM1 | |
| Hydrochloric Acid SCHEMBL29475075 | 0.89 | PARP1 (0.52) | HPGDSKCNH2HDAC2HDAC3OPRM1 | |
| Trifluoroacetic Acid SCHEMBL6824156 | 0.84 | ALDH1A1 (0.59) | HPGDSKCNH2HDAC2HDAC3HRH4 | |
| Trifluoroacetic Acid SCHEMBL30349693 | 0.84 | OPRM1 (0.48) | HPGDSOPRM1OPRK1PARP1SMO | |
| SCHEMBL1896186 | 0.81 | KCNH2 (0.53) | HPGDSKCNH2HDAC2HDAC3HDAC1 | |
| Trifluoroacetic Acid SCHEMBL6392063 | 0.80 | ALDH1A1 (0.57) | PARP1 | |
| Hydrochloric Acid SCHEMBL31552815 | 0.79 | KCNH2 (0.52) | HPGDSKCNH2HDAC2HDAC3HDAC1 | |
| SCHEMBL7547417 | 0.79 | KCNH2 (0.52) | HPGDSKCNH2HDAC2HDAC3HDAC1 | |
| SCHEMBL7550033 | 0.79 | KCNH2 (0.52) | HPGDSKCNH2HDAC2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230091225-A1 | Bifunctional chimeric heterocyclic compounds for targeted degradation of androgen receptors and use thereof | HINOVA PHARMACEUTICALS INC. (CN) | 2023-03-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230091225-A1 | Bifunctional chimeric heterocyclic compounds for targeted degradation of androgen receptors and use thereof | AR, ADRM1, PSMA1 | HPGDS 3172/4885KCNH2 4759/4885HDAC2 1722/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.