Tyrosol

Tyrosol

SCHEMBL303517

COC.OCCc1ccc(O)cc1

nearest known ligand 0.81

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 1/20 0.81
ESR1 P03372 4/20 0.59
ESR2 Q92731 2/20 0.59
CALM1 P0DP23 1/20 0.55
CYP4F2 P78329 2/20 0.53
CYP4A11 Q02928 2/20 0.53
ALDH1A1 P00352 4/20 0.50
ADRA2A P08913 3/20 0.50
SLC6A2 P23975 3/20 0.50
KDM4E B2RXH2 3/20 0.50
BACE1 P56817 2/20 0.50
HTR1A P08908 1/20 0.50
CYP2C19 P33261 1/20 0.50
HTR3A P46098 1/20 0.50
TAAR1 Q96RJ0 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
TMEM97 Q5BJF2 1/20 0.50
SIGMAR1 Q99720 1/20 0.50
ADORA3 P0DMS8 2/20 0.48
TACR2 P21452 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tyrosol SCHEMBL43838 0.90 CA2 (1.00) CA2ESR1ESR2ALDH1A1ADRA2A
Tyrosol SCHEMBL28157257 0.87 CA2 (0.94) CA2ESR1ESR2ALDH1A1ADRA2A
Tyrosol SCHEMBL27940319 0.87 CA2 (0.94) CA2ESR1ESR2ALDH1A1ADRA2A
Tyrosol SCHEMBL28609607 0.87 CA2 (0.94) CA2ESR1ESR2ALDH1A1ADRA2A
SCHEMBL10458523 0.83 CA2 (0.85) CA2ESR1ESR2ALDH1A1ADRA2A
SCHEMBL6817399 0.81 CA2 (0.58) CA2ESR1ESR2CALM1CYP4F2
Tyrosol SCHEMBL11040022 0.80 CA2 (0.71) CA2ESR1ESR2CYP4F2CYP4A11
Methoxymethane SCHEMBL28116150 0.79 ESR1 (0.76) CA2ESR1ESR2CALM1ALDH1A1
SCHEMBL40656 0.79 CA2 (0.77) CA2ESR1ESR2CYP4F2CYP4A11
SCHEMBL28001754 0.79 CA2 (0.68) CA2ESR1ESR2CALM1CYP4F2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 70 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2315739-B1 NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L P (US) 2014-11-12 EP claimed
US-8163464-B2 Propanoates and processes for preparing the same Du Pont Electronic Polymers L.P. (US) 2012-04-24 US claimed
JP-2012500846-A 2012-01-12 JP claimed
EP-2336216-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same DuPont Electronic Polymers L.P. (US) 2011-06-22 EP claimed
EP-2315739-A1 NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME DuPont Electronic Polymers L.P. (US) 2011-05-04 EP claimed
JP-4629097-B2 2011-02-09 JP claimed
US-20100105785-A1 Derivatized polyhydroxystyrenes (DPHS) with a novolak type structure and blocked DPHS (BDPHS) and processes for preparing the same SHEEHAN MICHAEL T 2010-04-29 US claimed
US-7678945-B2 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same DUPONT ELECTRONIC POLYMERS L.P. (US) 2010-03-16 US claimed
WO-2010024841-A1 NEW PROPANOATES AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L.P. (US) 2010-03-04 WO claimed
US-20100047714-A1 New propanoates and processes for preparing the same U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2010-02-25 US claimed
US-20080214874-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same SHEEHAN MICHAEL T 2008-09-04 US claimed
US-7371800-B2 Derivatized novolak polyhydroxystyrene from hydroxyphenylmethylcarbinol DUPONT ELECTRONIC POLYMERS L.P. (US) 2008-05-13 US claimed
EP-1756191-A1 DERIVATIZED POLYHYDROXYSTYRENES WITH A NOVOLAK TYPE STRUCTURE AND PROCESSES FOR PREPARING THE SAME Dupont Electronic Polymers L.P. (US) 2007-02-28 EP claimed
WO-2006052380-A1 DERIVATIZED POLYHYDROXYSTRYRENE (DPHS)WITH A NOVOLAK TYPE STRUCTURE AND BLOCKED DPHS (BDPHS) AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L.P. (US) 2006-05-18 WO claimed
US-20060099531-A1 Derivatized polyhydroxystyrenes (DPHS) with a novolak type structure and blocked DPHS (BDPHS) and processes for preparing the same U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2006-05-11 US claimed
WO-2005113634-A1 DERIVATIZED POLYHYDROXYSTYRENES WITH A NOVOLAK TYPE STRUCTURE AND PROCESSES FOR PREPARING THE SAME DUPONT ELECTRONIC POLYMERS L.P. (US) 2005-12-01 WO claimed
US-20050250042-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2005-11-10 US claimed
US-20230374213-A1 PROCESS FOR PREPARING BRANCHED PHENOLIC NOVOLAK ADVANCED POLYMER COATINGS, INC. (US) 2023-11-23 US disclosed
US-5565544-A POLYMERIZING A MIXTURE OF CARBOXYLIC ACID AND AT LEAST ONE SUSTITUTED PHENYL CARBINOL HOECHST CELANESE CORPORATION (US) 1996-10-15 US disclosed
US-5554719-A Polyhydroxystyrene with a novolak type structure HOECHST CELANESE CORPORATION (US) 1996-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100047714-A1 New propanoates and processes for preparing the same HPD, HMBS, LDHB CA2 1637/4885ESR1 1760/4885ESR2 2692/4885
US-20080214874-A1 Derivatized polyhydroxystyrenes with a novolak type structure and processes for preparing the same VRK1, VRK2, CHKB CA2 2666/4885ESR1 1023/4885ESR2 997/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.