Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 7/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 5/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.42 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.33 |
| ▸ | MELK | Q14680 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CTSD | P07339 | 1/20 | 0.33 |
| ▸ | CTSE | P14091 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL3042529 | 0.93 | OPRD1 (0.41) | SLC6A4SLC6A2SLC6A3KCNH2PDK1 | |
| SCHEMBL3033983 | 0.86 | ALDH1A1 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2OPRM1 | |
| SCHEMBL3041213 | 0.82 | CACNA1B (0.46) | SLC6A4SLC6A2SLC6A3KCNH2OPRM1 | |
| SCHEMBL3039337 | 0.81 | PDK1 (0.48) | SLC6A4SLC6A2SLC6A3KCNH2PDK1 | |
| Trifluoroacetic Acid SCHEMBL3032309 | 0.80 | OPRM1 (0.40) | SLC6A4SLC6A2SLC6A3KCNH2OPRD1 | |
| SCHEMBL3033986 | 0.79 | OPRM1 (0.49) | PDK1OPRD1OPRM1 | |
| SCHEMBL3032506 | 0.79 | OPRM1 (0.50) | SLC6A4SLC6A2SLC6A3PDK1OPRD1 | |
| SCHEMBL3029377 | 0.79 | PDK1 (0.48) | SLC6A4SLC6A2PDK1OPRD1OPRM1 | |
| SCHEMBL3035361 | 0.78 | OPRD1 (0.50) | SLC6A4SLC6A2SLC6A3KCNH2OPRD1 | |
| Trifluoroacetic Acid SCHEMBL3032574 | 0.78 | CACNA1B (0.42) | SLC6A4SLC6A2SLC6A3KCNH2OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2010-08-12 | — | — | US | claimed |
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | NEUROSEARCH A/S (DK) | 2010-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100204275-A1 | N-PIPERIDIN-4-YLMETHYL-AMIDE DERIVATIVES AND THEIR USE AS MONOAMINE NEUROTRANSMITTER RE-UPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | SLC6A4 5/4885SLC6A2 2/4885SLC6A3 11/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.