Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.56 |
| ▸ | MMP9 | P14780 | 1/20 | 0.56 |
| ▸ | MMP8 | P22894 | 1/20 | 0.56 |
| ▸ | MMP13 | P45452 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | CASP3 | P42574 | 1/20 | 0.52 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.52 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.52 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | XDH | P47989 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29151231 | 1.00 | MMP2 (0.56) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL10547054 | 0.81 | NPC1 (0.59) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL29151300 | 0.81 | MMP2 (0.46) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL30354878 | 0.81 | MMP2 (0.46) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL30354973 | 0.80 | L3MBTL1 (0.53) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL29151278 | 0.80 | L3MBTL1 (0.53) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL30354950 | 0.79 | RAB9A (0.60) | LMNAMAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9732366 | 0.77 | ALDH1A1 (0.51) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL9732375 | 0.77 | ADRB1 (0.53) | MMP2MMP9MMP8MMP13LMNA | |
| SCHEMBL5757008 | 0.76 | NPC1 (0.53) | LMNAMAPTNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115955968-A | Carbohydrazone acyldinitrile compounds comprising at least two aryl or heteroaryl groups connected by a novel linker and uses thereof | 韩国科学技术研究院 | 2023-04-11 | — | — | CN | disclosed |