Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | SI | P14410 | 1/20 | 0.42 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682664 | 1.00 | POLB (0.58) | POLBALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL30356525 | 0.85 | POLB (0.46) | POLBALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL6558564 | 0.84 | ALDH1A1 (0.53) | POLBALDH1A1MAPTRAB9ASMN1; SMN2 | |
| SCHEMBL29025711 | 0.81 | POLB (0.45) | POLBALDH1A1ERCC5FEN1PLAU | |
| SCHEMBL29025637 | 0.80 | POLB (0.46) | POLBALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL30356535 | 0.80 | POLB (0.46) | POLBALDH1A1MAPTSMN1; SMN2KMT2A | |
| SCHEMBL29025627 | 0.75 | POLB (0.42) | POLBALDH1A1MAPTHSP90AA1PLAU | |
| SCHEMBL30356530 | 0.75 | POLB (0.42) | POLBALDH1A1MAPTHSP90AA1PLAU | |
| SCHEMBL21821207 | 0.74 | PLAU (0.51) | POLBALDH1A1RAB9ASMN1; SMN2GAA | |
| SCHEMBL30817843 | 0.73 | HMOX1 (0.50) | POLBALDH1A1MAPTRAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-120136801-A | Preparation method of (R) -1- (2-chlorophenyl) -2- (tetrazole-2-yl) ethyl carbamate | 浙江京新药业股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-120137923-A | Genetically engineered bacterium, method for synthesizing (R) -1- (2-chlorophenyl) -2- (2H-tetrazole-2-yl) ethanol by using genetically engineered bacterium and related enzyme | 浙江海正药业股份有限公司 | 2025-06-13 | — | — | CN | claimed |
| CN-119409653-A | Mechanical ball milling synthesis method of Cenobamate pharmaceutical intermediates | 浙江工业大学 | 2025-02-11 | — | — | CN | claimed |
| CN-121085862-A | Continuous synthesis method of 1- (2-chlorophenyl) -2- (2-tetrazolyl) ethanone | 翼思生物医药(苏州)有限公司 | 2025-12-09 | — | — | CN | disclosed |
| CN-121085862-A | Continuous synthesis method of 1- (2-chlorophenyl) -2- (2-tetrazolyl) ethanone | 翼思生物医药(苏州)有限公司 | 2025-12-09 | — | — | CN | disclosed |
| CN-121064117-A | Preparation method of 1- (2-chlorophenyl) -2- (2-tetrazolyl) ethanone | 翼思生物医药(苏州)有限公司 | 2025-12-05 | — | — | CN | disclosed |
| CN-121064117-A | Preparation method of 1- (2-chlorophenyl) -2- (2-tetrazolyl) ethanone | 翼思生物医药(苏州)有限公司 | 2025-12-05 | — | — | CN | disclosed |
| CN-120137923-A | Genetically engineered bacterium, method for synthesizing (R) -1- (2-chlorophenyl) -2- (2H-tetrazole-2-yl) ethanol by using genetically engineered bacterium and related enzyme | 浙江海正药业股份有限公司 | 2025-06-13 | — | — | CN | disclosed |
| CN-116143717-B | Deuterated carbamate compound and application thereof in medicine | 康百达（四川）生物医药科技有限公司 | 2025-05-06 | — | — | CN | disclosed |
| CN-119462544-A | Synthetic method of cinnolamine ester | 江苏艾立康医药科技有限公司 | 2025-02-18 | — | — | CN | disclosed |
| CN-119409653-A | Mechanical ball milling synthesis method of Cenobamate pharmaceutical intermediates | 浙江工业大学 | 2025-02-11 | — | — | CN | disclosed |
| CN-115974799-B | Carbamate substituted alcohol derivative and application thereof in medicine | 成都百裕制药股份有限公司 | 2024-08-13 | — | — | CN | disclosed |
| CN-117736157-A | Preparation method of tetrazole-substituted acetophenone compound | 江苏恩华药业股份有限公司 | 2024-03-22 | — | — | CN | disclosed |
| CN-116143717-A | Deuterated carbamate compound and application thereof in medicine | 成都百裕制药股份有限公司 | 2023-05-23 | — | — | CN | disclosed |
| CN-115974799-A | Carbamate substituted alcohol derivatives and their use in medicine | 成都百裕制药股份有限公司 | 2023-04-18 | — | — | CN | disclosed |