Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMOX1 | P09601 | 1/20 | 0.50 |
| ▸ | ALPG | P10696 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.44 |
| ▸ | FEN1 | P39748 | 1/20 | 0.44 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1682667 | 1.00 | HMOX1 (0.50) | HMOX1ALPGALDH1A1MAPTKMT2A | |
| SCHEMBL6556662 | 0.84 | MAPK1 (0.53) | ALPGALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL7792067 | 0.78 | ALPG (0.61) | HMOX1ALPGALDH1A1MAPTKMT2A | |
| SCHEMBL9714015 | 0.76 | LMNA (0.49) | ALDH1A1MAPTKMT2AMEN1HSD17B10 | |
| SCHEMBL21821206 | 0.73 | PLAU (0.54) | ALDH1A1KMT2AMEN1HSD17B10KDM4E | |
| SCHEMBL30356468 | 0.73 | POLB (0.58) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL1682664 | 0.73 | POLB (0.58) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL30093208 | 0.71 | KCNH2 (0.51) | HMOX1ALPGALDH1A1HSD17B10POLB | |
| SCHEMBL29669830 | 0.70 | CA12 (0.56) | ALPGKDM4E | |
| SCHEMBL10878611 | 0.70 | CA12 (0.56) | ALPGKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117736157-A | Preparation method of tetrazole-substituted acetophenone compound | 江苏恩华药业股份有限公司 | 2024-03-22 | — | — | CN | disclosed |