Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | CES2 | O00748 | 1/20 | 0.47 |
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30356468 | 0.74 | POLB (0.58) | PLAUELANEKMT2ACES2CES1 | |
| SCHEMBL1682664 | 0.74 | POLB (0.58) | PLAUELANEKMT2ACES2CES1 | |
| SCHEMBL21821206 | 0.71 | PLAU (0.54) | PLAUELANEKMT2ACES2CES1 | |
| SCHEMBL13307717 | 0.71 | RAB9A (0.49) | PLAUELANEKMT2ACES2CES1 | |
| SCHEMBL10723816 | 0.68 | RAB9A (0.80) | KMT2AALDH1A1MEN1RXFP1RAB9A | |
| SCHEMBL9426932 | 0.67 | ALDH1A1 (0.57) | PLAUELANEKMT2ACES2CES1 | |
| SCHEMBL2325272 | 0.66 | CES2 (0.65) | KMT2ACES2CES1ALDH1A1MEN1 | |
| SCHEMBL50416 | 0.66 | CES2 (0.71) | KMT2ACES2CES1ALDH1A1POLB | |
| SCHEMBL7381738 | 0.66 | — | — | |
| SCHEMBL31544074 | 0.66 | CES2 (1.00) | KMT2ACES2CES1ALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118221604-A | Process for preparing aryl 2-tetrazol-2-yl ketones with improved selectivity | 爱思开生物制药株式会社 | 2024-06-21 | — | — | CN | disclosed |
| CN-114901647-B | Process for preparing aryl 2-tetrazol-2-yl ketones with improved selectivity | 爱思开生物制药株式会社 | 2024-04-02 | — | — | CN | disclosed |
| EP-4048658-A1 | METHOD FOR PREPARING ARYL 2-TETRAZOL-2-YL KETONE WITH IMPROVED SELECTIVITY | SK Biopharmaceuticals Co., Ltd. (KR) | 2022-08-31 | — | — | EP | disclosed |
| CN-114901647-A | Method for producing aryl 2-tetrazol-2-yl ketones with improved selectivity | 爱思开生物制药株式会社 | 2022-08-12 | — | — | CN | disclosed |
| US-11236054-B2 | Method for preparing aryl 2-tetrazol-1-yl keto with improved selectivity | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2022-02-01 | — | — | US | disclosed |
| WO-2021080380-A1 | METHOD FOR PREPARING ARYL 2-TETRAZOL-2-YL KETONE WITH IMPROVED SELECTIVITY | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2021-04-29 | — | — | WO | disclosed |
| US-20210122719-A1 | Method For Preparing Aryl 2-Tetrazol-1-Yl Keto With Improved Selectivity | SK BIOPHARMACEUTICALS CO., LTD. | 2021-04-29 | — | — | US | disclosed |
| US-10611737-B1 | Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity | SK BIOPHARMACEUTICALS CO., LTD. (KR) | 2020-04-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122719-A1 | Method For Preparing Aryl 2-Tetrazol-1-Yl Keto With Improved Selectivity | KARS1, TYK2, KYAT1 | PLAU 4261/4885ELANE 4742/4885KMT2A 273/4885 |
| US-11236054-B2 | Method for preparing aryl 2-tetrazol-1-yl keto with improved selectivity | KARS1, TYK2, KYAT1 | PLAU 4261/4885ELANE 4742/4885KMT2A 273/4885 |
| US-10611737-B1 | Method for preparing aryl 2-tetrazol-2-yl ketone with improved selectivity | KARS1, TYK2, TTL | PLAU 4008/4885ELANE 4688/4885KMT2A 280/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.