Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 11/20 | 0.43 |
| ▸ | PDE3A | Q14432 | 11/20 | 0.43 |
| ▸ | PDE2A | O00408 | 8/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.36 |
| ▸ | APAF1 | O14727 | 1/20 | 0.35 |
| ▸ | CASP6 | P55212 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | P2RY12 | Q9H244 | 3/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29349996 | 0.74 | PDE3B (0.47) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL10006861 | 0.74 | PDE3B (0.47) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL30358089 | 0.72 | PDE3B (0.49) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL30358054 | 0.71 | PDE3B (0.44) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL2734677 | 0.69 | MAPK8 (0.38) | PDE3BPDE3AALDH1A1KDM4EGLA | |
| SCHEMBL3663241 | 0.67 | APAF1 (0.44) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL29361697 | 0.67 | APAF1 (0.44) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL29580870 | 0.67 | XDH (0.35) | — | |
| SCHEMBL20157445 | 0.67 | PDE3B (0.45) | PDE3BPDE3APDE2AALDH1A1KDM4E | |
| SCHEMBL31465468 | 0.66 | XDH (0.41) | PDE3BPDE3APDE2AHPGDADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | KANGBAIDA (SICHUAN) BIOTECHNOLOGY CO., LTD. (CN) | 2023-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165867-A1 | IMIDAZOLIDINONE DERIVATIVES AND MEDICAL USE THEREOF | SYMPK, PAICS, CYP2C9 | PDE3B 447/4885PDE3A 209/4885PDE2A 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.