Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.82 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | KARS1 | Q15046 | 4/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.41 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.41 |
| ▸ | ITGAL | P20701 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30894568 | 0.90 | RXRA (0.66) | RXRANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30894572 | 0.90 | RXRA (0.66) | RXRANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30367547 | 0.90 | RXRA (0.82) | RXRANPC1RAB9ASMN1; SMN2ITGB2 | |
| SCHEMBL30894584 | 0.85 | RXRA (0.59) | RXRANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30366603 | 0.83 | RXRA (0.71) | RXRANPC1RAB9ASMN1; SMN2ITGB2 | |
| SCHEMBL30367096 | 0.83 | RXRA (0.61) | RXRARAB9AKARS1ITGB2ICAM1 | |
| SCHEMBL30366881 | 0.82 | RXRA (0.85) | RXRANPC1RAB9ASMN1; SMN2ITGB2 | |
| SCHEMBL30894580 | 0.81 | RXRA (0.54) | RXRAKARS1MAPTALDH1A1MMP1 | |
| SCHEMBL30894579 | 0.80 | RXRA (0.80) | RXRANPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL30366978 | 0.76 | WNT3A (0.56) | RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |