Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 1/20 | 0.58 |
| ▸ | WNT3A | P56704 | 4/20 | 0.45 |
| ▸ | GSK3B | P49841 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 2/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.44 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | ITGB2 | P05107 | 2/20 | 0.43 |
| ▸ | ICAM1 | P05362 | 2/20 | 0.43 |
| ▸ | ITGAL | P20701 | 2/20 | 0.43 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.42 |
| ▸ | KARS1 | Q15046 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | CLK3 | P49761 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367152 | 0.93 | WNT3A (0.54) | RXRAWNT3A | |
| SCHEMBL30366840 | 0.90 | TRPV1 (0.50) | RXRAWNT3AGSK3BPRKACAROCK1 | |
| SCHEMBL30367096 | 0.89 | RXRA (0.61) | RXRAWNT3AGSK3BKCNQ2ITGB2 | |
| SCHEMBL30366865 | 0.86 | RXRA (0.56) | RXRAPRKACAROCK1ITGB2ICAM1 | |
| SCHEMBL30366978 | 0.83 | WNT3A (0.56) | RXRAWNT3A | |
| SCHEMBL30367057 | 0.83 | WNT3A (0.57) | WNT3AGSK3BWNT1CLK2CLK3 | |
| SCHEMBL30367158 | 0.82 | RXRA (0.66) | RXRAWNT3AGSK3BITGB2ICAM1 | |
| SCHEMBL31050200 | 0.81 | WNT3A (0.57) | RXRAWNT3APRKACAROCK1ITGB2 | |
| SCHEMBL30367547 | 0.81 | RXRA (0.82) | RXRAITGB2ICAM1ITGALMAPK14 | |
| SCHEMBL29083757 | 0.80 | RXRA (0.60) | RXRAGSK3BITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082310-B | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2024-08-20 | — | — | CN | disclosed |
| CN-116082310-A | Bipyridine amide derivative, and preparation and application thereof | 厦门大学 | 2023-05-09 | — | — | CN | disclosed |