Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR9 | Q9NR96 | 3/20 | 0.42 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.42 |
| ▸ | BTK | Q06187 | 12/20 | 0.41 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.40 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.40 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.39 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.39 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.39 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367097 | 0.80 | BTK (0.44) | TLR9TLR8BTKROCK2 | |
| SCHEMBL30367384 | 0.79 | MAPK1 (0.40) | TLR9TLR8ROCK2ROCK1TLR7 | |
| SCHEMBL30367356 | 0.79 | DGAT1 (0.42) | TLR9TLR8TLR7DGAT1MAPK1 | |
| SCHEMBL30367296 | 0.77 | MAPK1 (0.39) | TLR9TLR8BTKTLR7DGAT1 | |
| Trifluoroacetic Acid SCHEMBL29052474 | 0.74 | DGAT1 (0.44) | BTKDGAT1MAPK1 | |
| Trifluoroacetic Acid SCHEMBL30367156 | 0.74 | DGAT1 (0.44) | BTKDGAT1MAPK1 | |
| SCHEMBL30367699 | 0.72 | KDM1A (0.41) | TLR9TLR8DGAT1MAPK1 | |
| SCHEMBL30367711 | 0.71 | TLR9 (0.38) | TLR9TLR8BTKTLR7DGAT1 | |
| SCHEMBL30367527 | 0.70 | MERTK (0.38) | TLR9TLR8BTKMAPK1 | |
| SCHEMBL30367001 | 0.68 | DGAT1 (0.39) | TLR9TLR8BTKTLR7DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |