Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 1/20 | 0.40 |
| ▸ | TGM2 | P21980 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | PPARA | Q07869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2234378 | 0.89 | CTSK (0.47) | TYRCTSK | |
| SCHEMBL30460474 | 0.89 | CTSK (0.47) | TYRCTSK | |
| SCHEMBL22804081 | 0.89 | CTSK (0.47) | TYRCTSK | |
| SCHEMBL31005798 | 0.89 | CTSK (0.47) | TYRCTSK | |
| SCHEMBL27718876 | 0.89 | CTSK (0.47) | TYRCTSK | |
| SCHEMBL2549264 | 0.88 | PNMT (0.43) | PNMTTGM2NPC1RAB9AACE | |
| SCHEMBL2549268 | 0.88 | PNMT (0.43) | PNMTTGM2NPC1RAB9AACE | |
| SCHEMBL30904667 | 0.87 | CASP1 (0.46) | PNMTCASP1 | |
| SCHEMBL30122530 | 0.87 | CASP1 (0.46) | PNMTCASP1 | |
| SCHEMBL18689470 | 0.87 | PNMT (0.42) | PNMTTGM2NPC1RAB9AACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230120254-A1 | Nitrile-Containing Antiviral Compounds | PFIZER INC. (US) | 2023-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230120254-A1 | Nitrile-Containing Antiviral Compounds | ACE2, NOS2, EIF2AK2 | PNMT 284/4885TGM2 1435/4885NPC1 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.