SCHEMBL30367649

SCHEMBL30367649

CSc1cccc(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.44
ATM Q13315 1/20 0.44
CYP1A2 P05177 3/20 0.40
CYP3A4 P08684 2/20 0.40
HTR1A P08908 2/20 0.40
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40
HTR3A P46098 2/20 0.40
CYP2A6 P11509 1/20 0.39
TSHR P16473 2/20 0.38
ACHE P22303 1/20 0.38
ALDH1A1 P00352 3/20 0.38
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38
MAPT P10636 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
LMNA P02545 2/20 0.37
NOTUM Q6P988 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL700366 1.00 TRPA1 (0.44) TRPA1ATMCYP1A2CYP3A4HTR1A
SCHEMBL3014828 0.86 ALDH1A1 (0.40) CYP3A4TSHRACHEALDH1A1MAPT
Ammonia Solution, Strong SCHEMBL7190297 0.83 ALDH1A1 (0.39) CYP3A4TSHRACHEALDH1A1MAPT
SCHEMBL29589002 0.81 HTR1A (0.53) TRPA1ATMCYP1A2CYP3A4HTR1A
SCHEMBL576045 0.81 HTR1A (0.53) TRPA1ATMCYP1A2CYP3A4HTR1A
SCHEMBL29687933 0.81 HTR1A (0.53) TRPA1ATMCYP1A2CYP3A4HTR1A
SCHEMBL576522 0.81 TRPA1 (0.46) TRPA1ATMCYP1A2CYP3A4HTR1A
SCHEMBL29722887 0.78
SCHEMBL407202 0.78
SCHEMBL2320126 0.77 CYP2A6 (0.38) TRPA1ATMCYP1A2CYP2A6TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116947716-A Preparation method of 2, 3-dimethyl-4-methylsulfonyl methyl benzoate 绍兴贝斯美化工股份有限公司 2023-10-27 CN claimed
CN-116947775-A Preparation method of 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4-methylsulfonyl methyl benzoate 绍兴贝斯美化工股份有限公司 2023-10-27 CN claimed
CN-116947716-A Preparation method of 2, 3-dimethyl-4-methylsulfonyl methyl benzoate 绍兴贝斯美化工股份有限公司 2023-10-27 CN disclosed
CN-116947775-A Preparation method of 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4-methylsulfonyl methyl benzoate 绍兴贝斯美化工股份有限公司 2023-10-27 CN disclosed
CN-115970605-A Device and method for continuously preparing 2,3-dimethyl phenyl sulfide 沈阳化工研究院有限公司 2023-04-18 CN disclosed