SCHEMBL3014828

SCHEMBL3014828

CSc1cccc(SC)c1C

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.40
SMN1; SMN2 Q16637 3/20 0.40
MAPT P10636 3/20 0.40
GRM5 P41594 1/20 0.37
CYP3A4 P08684 1/20 0.36
TSHR P16473 1/20 0.36
PIK3CA P42336 1/20 0.36
KMT2A Q03164 3/20 0.33
MEN1 O00255 2/20 0.33
KDM4E B2RXH2 2/20 0.33
LMNA P02545 2/20 0.33
CCR1 P32246 1/20 0.33
CCR8 P51685 1/20 0.33
ACHE P22303 1/20 0.33
IDO1 P14902 1/20 0.33
NPC1 O15118 1/20 0.33
HPGD P15428 1/20 0.33
RAB9A P51151 1/20 0.33
NPSR1 Q6W5P4 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Ammonia Solution, Strong SCHEMBL7190297 0.97 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPTGRM5CYP3A4
SCHEMBL30367649 0.86 TRPA1 (0.44) ALDH1A1SMN1; SMN2MAPTGRM5CYP3A4
SCHEMBL700366 0.86 TRPA1 (0.44) ALDH1A1SMN1; SMN2MAPTGRM5CYP3A4
SCHEMBL2783311 0.82 ALDH1A1 (0.39) ALDH1A1SMN1; SMN2MAPTGRM5KDM4E
SCHEMBL28937929 0.82 SLC6A2 (0.40) ALDH1A1SMN1; SMN2MAPTGRM5TSHR
SCHEMBL7463021 0.82 CYP3A4 (0.59) ALDH1A1SMN1; SMN2MAPTGRM5CYP3A4
SCHEMBL16956557 0.82 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2MAPTGRM5
SCHEMBL17384528 0.82 ACHE (0.39) ALDH1A1SMN1; SMN2MAPTGRM5KMT2A
SCHEMBL4030686 0.82 MAPT (0.54) ALDH1A1SMN1; SMN2MAPTCYP3A4TSHR
SCHEMBL13696441 0.78 POLB (0.46) ALDH1A1SMN1; SMN2MAPTCYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8951713-B2 Alkali-soluble resin and negative-type photosensitive resin composition comprising the same LG CHEM, LTD. (KR) 2015-02-10 US claimed
US-20130130176-A1 ALKALI-SOLUBLE RESIN AND NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2013-05-23 US claimed
US-20100196824-A1 ALKALI-SOLUBLE RESIN AND NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2010-08-05 US claimed
WO-2009054620-A2 ALKALI-SOLUBLE RESIN AND NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM. LTD. (KR) 2009-04-30 WO claimed
CN-113501938-B Room temperature Stille-like cross-coupling copolymerization based on D-A conjugated polymer semiconductor 中国科学院大学 2023-10-13 CN disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-09-14 US disclosed
CN-114989399-B Room temperature Suzuki cross-coupling polymerization method of conjugated polymer semiconductor material 中国科学院大学 2023-08-01 CN disclosed
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-01-05 US disclosed
US-9617255-B2 Organic electroluminescent element, and illumination device and display device each comprising the element Konica Minolta, Inc. (JP) 2017-04-11 US disclosed
US-8951713-B2 Alkali-soluble resin and negative-type photosensitive resin composition comprising the same LG CHEM, LTD. (KR) 2015-02-10 US disclosed
US-8852757-B2 Organic electroluminescence element, lighting device and display device KONICA MINOLTA HOLDINGS, INC. (JP) 2014-10-07 US disclosed
US-20130130176-A1 ALKALI-SOLUBLE RESIN AND NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2013-05-23 US disclosed
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME KONICA MINOLTA HOLDINGS, INC. (JP) 2011-01-13 US disclosed
US-20100196824-A1 ALKALI-SOLUBLE RESIN AND NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM, LTD. (KR) 2010-08-05 US disclosed
US-20100045171-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE KONICA MINOLTA HOLDINGS, INC. (JP) 2010-02-25 US disclosed
WO-2009054620-A2 ALKALI-SOLUBLE RESIN AND NEGATIVE-TYPE PHOTOSENSITIVE RESIN COMPOSITION COMPRISING THE SAME LG CHEM. LTD. (KR) 2009-04-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230287011-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OXGR1, OCIAD1 ALDH1A1 983/4885SMN1; SMN2 3545/4885MAPT 1880/4885
US-20230002417-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, ODC1 ALDH1A1 81/4885SMN1; SMN2 4286/4885MAPT 1951/4885
US-20110006670-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME AOC2, AOC3, CDYL ALDH1A1 54/4885SMN1; SMN2 4070/4885MAPT 4583/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.