Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPA1 | O75762 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HTR3A | P46098 | 2/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367649 | 1.00 | TRPA1 (0.44) | TRPA1ATMCYP1A2CYP3A4HTR1A | |
| SCHEMBL3014828 | 0.86 | ALDH1A1 (0.40) | CYP3A4TSHRACHEALDH1A1MAPT | |
| Ammonia Solution, Strong SCHEMBL7190297 | 0.83 | ALDH1A1 (0.39) | CYP3A4TSHRACHEALDH1A1MAPT | |
| SCHEMBL29589002 | 0.81 | HTR1A (0.53) | TRPA1ATMCYP1A2CYP3A4HTR1A | |
| SCHEMBL576045 | 0.81 | HTR1A (0.53) | TRPA1ATMCYP1A2CYP3A4HTR1A | |
| SCHEMBL29687933 | 0.81 | HTR1A (0.53) | TRPA1ATMCYP1A2CYP3A4HTR1A | |
| SCHEMBL576522 | 0.81 | TRPA1 (0.46) | TRPA1ATMCYP1A2CYP3A4HTR1A | |
| SCHEMBL29722887 | 0.78 | — | — | |
| SCHEMBL407202 | 0.78 | — | — | |
| SCHEMBL2320126 | 0.77 | CYP2A6 (0.38) | TRPA1ATMCYP1A2CYP2A6TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947716-A | Preparation method of 2, 3-dimethyl-4-methylsulfonyl methyl benzoate | 绍兴贝斯美化工股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-116947775-A | Preparation method of 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4-methylsulfonyl methyl benzoate | 绍兴贝斯美化工股份有限公司 | 2023-10-27 | — | — | CN | claimed |
| CN-115970605-A | Device and method for continuously preparing 2,3-dimethyl phenyl sulfide | 沈阳化工研究院有限公司 | 2023-04-18 | — | — | CN | claimed |
| CN-114088862-A | Analysis method for content of 2, 3-dimethyl sulfide | 京博农化科技有限公司 | 2022-02-25 | — | — | CN | claimed |
| CN-118146125-A | Method for synthesizing topramezone intermediate 2, 3-dimethyl sulfide by copper catalysis | 江苏中旗科技股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-116947716-A | Preparation method of 2, 3-dimethyl-4-methylsulfonyl methyl benzoate | 绍兴贝斯美化工股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116947775-A | Preparation method of 3- (4, 5-dihydro-3-isoxazolyl) -2-methyl-4-methylsulfonyl methyl benzoate | 绍兴贝斯美化工股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| US-11787813-B2 | Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (USP1) inhibitors | KSQ Therapeutics, Inc. (US) | 2023-10-17 | — | — | US | disclosed |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | COGNITION THERAPEUTICS, INC. (US) | 2023-07-04 | — | — | US | disclosed |
| US-20230203046-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | KSQ Therapeutics, Inc. | 2023-06-29 | — | — | US | disclosed |
| CN-115970605-A | Device and method for continuously preparing 2,3-dimethyl phenyl sulfide | 沈阳化工研究院有限公司 | 2023-04-18 | — | — | CN | disclosed |
| EP-4023294-A1 | ISOINDOLINE COMPOSITIONS AND METHODS FOR TREATING ALZHEIMER'S DISEASE | Cognition Therapeutics, Inc. (US) | 2022-07-06 | — | — | EP | disclosed |
| US-6469176-B1 | CROP PROTECTION COMPOUNDS | BASF AKTIENGESELLSCHAFT (DE) | 2002-10-22 | — | — | US | disclosed |
| US-20020032230-A1 | Novel compounds having antiinflamatory activity: process for their preparation and pharmaceutical compositions containing them | DR. REDDY'S LABORATORIES LTD. | 2002-03-14 | — | — | US | disclosed |
| WO-2001090097-A2 | NOVEL COMPOUNDS HAVING ANTIINFLAMMATORY ACTIVITY: PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2001-11-29 | — | — | WO | disclosed |
| EP-1129082-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2001-09-05 | — | — | EP | disclosed |
| CN-1300284-A | Preparation of isoxazolin-3-yl-acylbenzenes | BASF AG (DE) | 2001-06-20 | — | — | CN | disclosed |
| EP-1077955-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 2001-02-28 | — | — | EP | disclosed |
| WO-2000029394-A1 | METHOD AND NOVEL INTERMEDIATE PRODUCTS FOR PRODUCING ISOXAZOLIN-3-YL-ACYLBENZENES | BASF AKTIENGESELLSCHAFT (DE) | 2000-05-25 | — | — | WO | disclosed |
| WO-1999058509-A1 | METHOD FOR PRODUCING ISOXAZOLINE-3-YL-ACYL BENZENE | BASF AKTIENGESELLSCHAFT (DE) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11787813-B2 | Substituted pyrazolopyrimidines and substituted purines and their use as ubiquitin-specific-processing protease 1 (USP1) inhibitors | USP1, UPP1, USP2 | TRPA1 4618/4885ATM 1260/4885CYP1A2 942/4885 |
| US-11691947-B2 | Isoindoline compositions and methods for treating neurodegenerative disease | TMEM97, SLC18A2, PSD | TRPA1 2680/4885ATM 2769/4885CYP1A2 3107/4885 |
| US-20020032230-A1 | Novel compounds having antiinflamatory activity: process for their preparation and pharmaceutical compositions containing them | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, TPSAB1, ACE | TRPA1 2923/4885ATM 4301/4885CYP1A2 1528/4885 |
| US-20230203046-A1 | SUBSTITUTED PYRAZOLOPYRIMIDINES AND SUBSTITUTED PURINES AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS | USP1, UPP1, USP2 | TRPA1 4618/4885ATM 1260/4885CYP1A2 942/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.