Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.38 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.38 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30367296 | 0.70 | MAPK1 (0.39) | DGAT1TLR9TLR8TLR7NAMPT | |
| SCHEMBL30367384 | 0.69 | MAPK1 (0.40) | DGAT1TLR9TLR8TLR7NAMPT | |
| SCHEMBL30367356 | 0.69 | DGAT1 (0.42) | DGAT1TLR9TLR8TLR7NAMPT | |
| Trifluoroacetic Acid SCHEMBL29052474 | 0.69 | DGAT1 (0.44) | DGAT1PIK3CDMAPK1BTK | |
| Trifluoroacetic Acid SCHEMBL30367156 | 0.69 | DGAT1 (0.44) | DGAT1PIK3CDMAPK1BTK | |
| SCHEMBL30367699 | 0.68 | KDM1A (0.41) | DGAT1TLR9TLR8NAMPTCCR1 | |
| SCHEMBL30367172 | 0.68 | TLR9 (0.38) | DGAT1TLR9TLR8TLR7NAMPT | |
| SCHEMBL30367399 | 0.68 | TLR9 (0.42) | DGAT1TLR9TLR8TLR7MAPK1 | |
| SCHEMBL27282972 | 0.67 | KDM4E (0.59) | DGAT1TLR9TLR8TLR7NAMPT | |
| SCHEMBL30367867 | 0.65 | KDM4E (0.40) | TLR9TLR8NAMPTCCR1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023155886-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-08-24 | — | — | WO | disclosed |
| CN-116437918-A | Pyrazolopyridine compounds as TAM inhibitors | 上海德琪医药科技有限公司 | 2023-07-14 | — | — | CN | disclosed |
| WO-2023051464-A1 | PYRAZOLOPYRIDINE COMPOUNDS AS TAM INHIBITORS | SHANGHAI ANTENGENE CORPORATION LIMITED (CN) | 2023-04-06 | — | — | WO | disclosed |