Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 2/20 | 0.44 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 2/20 | 0.42 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.41 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.39 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4599304 | 0.83 | HSD11B1 (0.59) | HSD11B1ALDH1A1HCRTR1HCRTR2TSHR | |
| SCHEMBL3092100 | 0.80 | HSD11B1 (0.56) | HSD11B1ALDH1A1HCRTR1HCRTR2CNR1 | |
| SCHEMBL29482199 | 0.79 | CNR1 (0.58) | HSD11B1ALDH1A1CNR1TSHRMEN1 | |
| SCHEMBL28812724 | 0.79 | RXFP1 (0.60) | HSD11B1ALDH1A1HCRTR1HCRTR2 | |
| SCHEMBL15058808 | 0.77 | RXFP1 (0.62) | HSD11B1ALDH1A1CYP2C9CYP2C19MEN1 | |
| SCHEMBL2022309 | 0.75 | HSP90AA1 (0.54) | HSD11B1ALDH1A1HCRTR1HCRTR2CYP2C9 | |
| Trifluoroacetic Acid SCHEMBL5255358 | 0.74 | RXFP1 (0.51) | HSD11B1ALDH1A1HCRTR1HCRTR2CYP2D6 | |
| SCHEMBL20472685 | 0.74 | CNR1 (0.44) | HSD11B1ALDH1A1CYP2C19CNR1P2RX7 | |
| SCHEMBL16000518 | 0.74 | HSD11B1 (0.57) | HSD11B1ALDH1A1HCRTR1HCRTR2CYP2D6 | |
| SCHEMBL16002964 | 0.73 | HSD11B1 (0.59) | HSD11B1ALDH1A1HCRTR1HCRTR2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230174484-A1 | ANTAGONISTS OF GPR39 PROTEIN | UNIV OREGON HEALTH & SCIENCE (US) | 2023-06-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230174484-A1 | ANTAGONISTS OF GPR39 PROTEIN | GPR39, GPR139, GPR119 | HSD11B1 2549/4885ALDH1A1 3167/4885HCRTR1 450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.