Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | F2 | P00734 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.34 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | LOX | P28300 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | XBP1 | P17861 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3885747 | 0.85 | MAOB (0.42) | ALDH1A1MAPTS1PR4MAOBHSD17B10 | |
| SCHEMBL8820277 | 0.84 | HDAC7 (0.41) | KDM4EALDH1A1MAPTPTGDR2KMT2A | |
| SCHEMBL2315622 | 0.83 | MAOB (0.49) | KDM4EALDH1A1MAPTHPGDMAOB | |
| SCHEMBL6236657 | 0.81 | CHRM1 (0.43) | KMT2ASMN1; SMN2NPSR1 | |
| SCHEMBL3151094 | 0.80 | HDAC7 (0.49) | KDM4EALDH1A1MAPTPTGDR2KMT2A | |
| SCHEMBL776571 | 0.79 | MAPT (0.44) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL9547090 | 0.79 | ALPL (0.47) | KDM4EALDH1A1MAPTGAAHPGD | |
| SCHEMBL8082279 | 0.78 | MAOA (0.41) | KDM4EALDH1A1MAPTPTGDR2KMT2A | |
| SCHEMBL11587245 | 0.77 | S1PR4 (0.45) | KDM4EALDH1A1MAPTS1PR4GAA | |
| SCHEMBL1117961 | 0.76 | PTGS2 (0.42) | KDM4EALDH1A1F2MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115996907-A | Inhibitors of MLH1 and/or PMS2 for cancer treatment | 奈奥芬莱有限公司 | 2023-04-21 | — | — | CN | disclosed |