Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | GLA | P06280 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | GSTA1 | P08263 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL638047 | 1.00 | MAPT (0.63) | MAPTPOLBKDM4EGLAALDH1A1 | |
| SCHEMBL2703001 | 0.89 | MAPT (0.56) | MAPTPOLBKDM4EGLAALDH1A1 | |
| SCHEMBL3549901 | 0.83 | MAPT (0.58) | MAPTPOLBKDM4EGLAALDH1A1 | |
| SCHEMBL3908082 | 0.83 | MAPT (0.58) | MAPTPOLBKDM4EGLAALDH1A1 | |
| SCHEMBL30089256 | 0.83 | MAPT (0.58) | MAPTPOLBKDM4EGLAALDH1A1 | |
| SCHEMBL2703087 | 0.83 | KEAP1 (0.59) | MAPTKDM4EALDH1A1TP53MAPK1 | |
| SCHEMBL5282720 | 0.82 | MAPT (0.59) | MAPTALDH1A1TP53NPC1HPGD | |
| SCHEMBL29664874 | 0.82 | MAPT (0.59) | MAPTALDH1A1TP53NPC1HPGD | |
| SCHEMBL28171560 | 0.81 | KDM4E (0.73) | MAPTPOLBKDM4EGLAALDH1A1 | |
| SCHEMBL332634 | 0.80 | RECQL (0.71) | MAPTPOLBKDM4EGLAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260125388-A1 | GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL SMOOTH MUSCLE CONTRACTION AND INFLAMMATION | UWM RES FOUNDATION INC (US) | 2026-05-07 | — | — | US | disclosed |
| CN-119192183-A | Benzodiazepines class of compounds and uses thereof | 中国药科大学 | 2024-12-27 | — | — | CN | disclosed |
| CN-116102558-A | Novel benzodiazepine compound, preparation method and application thereof | 中国药科大学 | 2023-05-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260125388-A1 | GABA(A) RECEPTOR MODULATORS AND METHODS TO CONTROL SMOOTH MUSCLE CONTRACTION AND INFLAMMATION | GABRB1, GABRA1, GABRB2 | MAPT 3864/4885POLB 3602/4885KDM4E 1863/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.