SCHEMBL30375290

SCHEMBL30375290

Cc1ccc(O)c(Cc2cc(CC(c3ccc(C(C)(C)c4cc(Cc5cc(C)ccc5O)c(O)c(Cc5cc(C)ccc5O)c4)cc3)c3cc(Cc4cc(C)ccc4O)c(O)c(Cc4cc(C)ccc4O)c3)cc(Cc3cc(C)ccc3O)c2O)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AMY1A P0DUB6 1/20 0.50
KLF10 Q13118 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.35
CYP2C9 P11712 2/20 0.35
CYP2C19 P33261 2/20 0.35
HIF1A Q16665 2/20 0.35
ESR1 P03372 3/20 0.34
MAPK1 P28482 2/20 0.34
MEN1 O00255 1/20 0.34
USP2 O75604 1/20 0.34
TP53 P04637 1/20 0.34
PGR P06401 1/20 0.34
CYP3A4 P08684 1/20 0.34
ADORA3 P0DMS8 1/20 0.34
AR P10275 1/20 0.34
MAPT P10636 1/20 0.34
DRD1 P21728 1/20 0.34
PTGS1 P23219 1/20 0.34
SLC6A2 P23975 1/20 0.34
PDE4A P27815 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30374864 0.84 ESR1 (0.41) KLF10ESR1MAPK1ARCACNA1B
SCHEMBL30374981 0.84 ESR1 (0.41) KLF10ESR1MAPK1CACNA1BALOX15
SCHEMBL30375421 0.83 SHBG (0.35) KLF10ESR1MAPK1ALOX15HTT
SCHEMBL30899196 0.82 ESR1 (0.38) KLF10ESR1MAPK1CYP3A4AR
SCHEMBL4057184 0.82 AMY1A (0.74) AMY1AKLF10SMN1; SMN2CYP2C9CYP2C19
SCHEMBL30375400 0.81 ESR1 (0.39) KLF10ESR1MAPK1MEN1CYP3A4
SCHEMBL9307036 0.81 CYP2D6 (0.47) AMY1AKLF10SMN1; SMN2CYP2C9CYP2C19
SCHEMBL30375252 0.81 KLF10 (0.32) KLF10ESR1MAPK1ALOX15HTT
SCHEMBL12299322 0.80 AMY1A (0.62) AMY1AKLF10SMN1; SMN2CYP2C9CYP2C19
SCHEMBL8755414 0.79 AMY1A (0.61) AMY1AKLF10SMN1; SMN2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed