SCHEMBL30375421

SCHEMBL30375421

Cc1cc(Cc2cc(CC(c3ccc(C(C)(C)c4cc(Cc5cc(C)c(O)c(C)c5)c(O)c(Cc5cc(C)c(O)c(C)c5)c4)cc3)c3cc(Cc4cc(C)c(O)c(C)c4)c(O)c(Cc4cc(C)c(O)c(C)c4)c3)cc(Cc3cc(C)c(O)c(C)c3)c2O)cc(C)c1O

nearest known ligand 0.35

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.35
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
KLF10 Q13118 1/20 0.32
ESR1 P03372 1/20 0.32
HMGB1 P09429 1/20 0.31
CXCL12 P48061 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30374864 0.90 ESR1 (0.41) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL27002552 0.87 ESR1 (0.39) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL30375400 0.87 ESR1 (0.39) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL30899196 0.85 ESR1 (0.38) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL30375252 0.83 KLF10 (0.32) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL30084871 0.83 ALOX15 (0.36) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL30375290 0.83 AMY1A (0.50) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL30374981 0.83 ESR1 (0.41) ALOX15MAPK1HTTKLF10ESR1
SCHEMBL5679013 0.82 ESR1 (0.44) SHBGESR1
SCHEMBL4066093 0.80 ALOX15 (0.50) SHBGALOX15MAPK1HTTKLF10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed