SCHEMBL30375400

SCHEMBL30375400

CC(C)(c1ccc(C(Cc2cc(Cc3ccc(O)cc3)c(O)c(Cc3ccc(O)cc3)c2)c2cc(Cc3ccc(O)cc3)c(O)c(Cc3ccc(O)cc3)c2)cc1)c1cc(Cc2ccc(O)cc2)c(O)c(Cc2ccc(O)cc2)c1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 13/20 0.39
ESR2 Q92731 13/20 0.39
CYP3A4 P08684 2/20 0.39
AR P10275 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
SLC6A2 P23975 1/20 0.39
SLC6A4 P31645 1/20 0.39
HTR6 P50406 1/20 0.39
ESRRG P62508 1/20 0.39
SLC6A3 Q01959 1/20 0.39
HSD17B10 Q99714 1/20 0.39
ALDH1A1 P00352 1/20 0.39
ALOX15 P16050 1/20 0.35
MAPK1 P28482 1/20 0.35
HTT P42858 1/20 0.35
KLF10 Q13118 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
HSPA5 P11021 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30375421 0.87 SHBG (0.35) ESR1ALOX15MAPK1HTTKLF10
SCHEMBL30374864 0.86 ESR1 (0.41) ESR1ESR2ARESRRGALOX15
SCHEMBL30374981 0.86 ESR1 (0.41) ESR1ESR2ALOX15MAPK1HTT
SCHEMBL30899196 0.86 ESR1 (0.38) ESR1ESR2CYP3A4ARHPGD
SCHEMBL5674846 0.84 ESR1 (0.43) ESR1ESR2MEN1KMT2AKEAP1
SCHEMBL30084871 0.84 ALOX15 (0.36) ESR1ESR2CYP3A4ARHPGD
SCHEMBL30375290 0.81 AMY1A (0.50) ESR1ESR2CYP3A4ARSLC6A2
SCHEMBL4058701 0.81 ALOX15 (0.50) ESR1ESR2CYP3A4ARHPGD
SCHEMBL30375252 0.80 KLF10 (0.32) ESR1ALOX15MAPK1HTTKLF10
SCHEMBL15475852 0.80 ESR1 (0.57) ESR1ESR2CYP3A4ARHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed