Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | VCP | P55072 | 1/20 | 0.54 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | LDHA | P00338 | 1/20 | 0.48 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19288664 | 1.00 | TSHR (0.61) | TSHRALDH1A1SMN1; SMN2VCPADRB1 | |
| SCHEMBL30564288 | 0.87 | TSHR (0.55) | TSHRALDH1A1SMN1; SMN2ADRB1DRD2 | |
| SCHEMBL1372927 | 0.85 | KCNH2 (0.69) | TSHRALDH1A1SMN1; SMN2ADRB1DRD2 | |
| SCHEMBL14528855 | 0.84 | TSHR (0.63) | TSHRALDH1A1SMN1; SMN2ADRB1DRD2 | |
| SCHEMBL24774008 | 0.82 | ALDH1A1 (0.59) | ALDH1A1SMN1; SMN2VCPADRB1KCNH2 | |
| SCHEMBL328244 | 0.82 | ADRA2C (0.71) | ALDH1A1SMN1; SMN2VCPKDM4EL3MBTL1 | |
| SCHEMBL27711751 | 0.82 | ADRB1 (0.68) | TSHRALDH1A1SMN1; SMN2ADRB1DRD2 | |
| SCHEMBL2635187 | 0.81 | VCP (0.58) | ALDH1A1SMN1; SMN2VCPL3MBTL1 | |
| SCHEMBL28330181 | 0.80 | L3MBTL1 (0.71) | ALDH1A1VCPDRD2KDM4EL3MBTL1 | |
| SCHEMBL23657330 | 0.79 | KCNH2 (0.61) | TSHRALDH1A1SMN1; SMN2ADRB1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023070114-A2 | REVERSIBLE LYSINE COVALENT MODIFIERS OF EGFR AND USES THEREOF | TERREMOTO BIOSCIENCES, INC. (US) | 2023-04-27 | — | — | WO | disclosed |