Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.37 |
| ▸ | PRKAA1 | Q13131 | 2/20 | 0.37 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.37 |
| ▸ | CISD1 | Q9NZ45 | 4/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | CA4 | P22748 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA5A | P35218 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30380768 | 1.00 | LMNA (0.38) | LMNAHCAR3TDP1PRKAG1PRKAA1 | |
| SCHEMBL30381149 | 0.85 | ALDH1A1 (0.45) | LMNAGAAALDH1A1NPSR1TP53 | |
| SCHEMBL30381068 | 0.85 | ALDH1A1 (0.45) | LMNAGAAALDH1A1NPSR1TP53 | |
| SCHEMBL30381186 | 0.73 | NFKB1 (0.36) | LMNAALDH1A1NPSR1TP53KMT2A | |
| Hydrochloric Acid SCHEMBL6181289 | 0.70 | P2RX7 (0.43) | TDP1PRKAG1PRKAA1PRKAB1ALDH1A1 | |
| SCHEMBL29066370 | 0.69 | LMNA (0.51) | LMNATDP1CISD1CA12CA1 | |
| SCHEMBL28710108 | 0.68 | ALDH1A1 (0.41) | LMNATDP1CISD1CA12CA1 | |
| SCHEMBL7683159 | 0.68 | SMN1; SMN2 (0.46) | TDP1CA1CA2ALDH1A1TP53 | |
| SCHEMBL14023609 | 0.68 | SORT1 (0.45) | LMNATDP1GABRPGABRDGABRA1 | |
| SCHEMBL30100715 | 0.68 | SORT1 (0.45) | LMNATDP1GABRPGABRDGABRA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023060173-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS, INC. (US) | 2023-04-13 | — | — | WO | disclosed |