Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | AGER | Q15109 | 1/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | RAD52 | P43351 | 1/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24169240 | 1.00 | ALDH1A1 (0.69) | ALDH1A1MAPTAGERKDM4EHPGD | |
| SCHEMBL16603972 | 0.82 | MAPT (1.00) | ALDH1A1MAPTAGERKDM4EHPGD | |
| SCHEMBL16604024 | 0.81 | RAD52 (0.74) | ALDH1A1MAPTKDM4ELMNARAD52 | |
| SCHEMBL16604015 | 0.74 | MAPT (0.74) | ALDH1A1MAPTAGERKDM4EHPGD | |
| SCHEMBL16604007 | 0.74 | AGER (0.55) | ALDH1A1MAPTAGERKDM4ELMNA | |
| SCHEMBL14706715 | 0.73 | RAD52 (0.64) | ALDH1A1MAPTKDM4ELMNARAD52 | |
| SCHEMBL12045404 | 0.73 | MEN1 (0.49) | ALDH1A1MAPTAGERKDM4EHPGD | |
| SCHEMBL6823233 | 0.73 | RAD52 (0.86) | ALDH1A1MAPTKDM4ELMNARAD52 | |
| SCHEMBL17482005 | 0.72 | RAD52 (0.56) | ALDH1A1MAPTKDM4ELMNARAD52 | |
| Hydrochloric Acid SCHEMBL9996066 | 0.72 | MEN1 (0.48) | ALDH1A1MAPTAGERKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260041687-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | PENN STATE RES FOUND (US) | 2026-02-12 | — | — | US | disclosed |
| US-12472185-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2025-11-18 | — | — | US | disclosed |
| US-11654146-B2 | Methods for killing antibiotic tolerant bacteria | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-05-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260041687-A1 | METHODS FOR KILLING ANTIBIOTIC TOLERANT BACTERIA | VDAC1, VDAC3, VIL1 | ALDH1A1 534/4885MAPT 3807/4885AGER 4604/4885 |
| US-11654146-B2 | Methods for killing antibiotic tolerant bacteria | CLPP, SPOUT1, CASP3 | ALDH1A1 942/4885MAPT 4525/4885AGER 4265/4885 |
| US-12472185-B2 | Methods for killing antibiotic tolerant bacteria | CLPP, SPOUT1, CASP3 | ALDH1A1 942/4885MAPT 4525/4885AGER 4265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.