Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT1 | P17948 | 1/20 | 0.49 |
| ▸ | ROR1 | Q01973 | 1/20 | 0.49 |
| ▸ | GRB2 | P62993 | 2/20 | 0.48 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | GRB7 | Q14451 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21430287 | 0.85 | HDAC3 (0.48) | — | |
| SCHEMBL22928930 | 0.85 | HDAC3 (0.48) | — | |
| Cyclomontanin D SCHEMBL30139332 | 0.81 | SLC6A3 (0.54) | FLT1GRB2 | |
| SCHEMBL31061607 | 0.80 | FLT1 (0.53) | FLT1GRB2 | |
| SCHEMBL13573536 | 0.80 | ITGB3 (0.51) | GRB7 | |
| SCHEMBL1370316 | 0.80 | CXCR4 (0.53) | — | |
| SCHEMBL21664109 | 0.77 | OPRM1 (0.49) | OPRM1OPRD1OPRK1 | |
| SCHEMBL31197219 | 0.77 | SOAT2 (0.53) | — | |
| SCHEMBL31197218 | 0.77 | SOAT2 (0.53) | — | |
| SCHEMBL29412929 | 0.77 | HDAC4 (0.54) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250295800-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | SAPREME TECH BV (NL) | 2025-09-25 | — | — | US | disclosed |
| EP-4452325-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | Sapreme Technologies B.V. (NL) | 2024-10-30 | — | — | EP | disclosed |
| US-20230302140-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | SAPREME TECHNOLOGIES B.V. (NL) | 2023-09-28 | — | — | US | disclosed |
| US-20230248844-A1 | COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE | SAPREME TECHNOLOGIES B.V. (NL) | 2023-08-10 | — | — | US | disclosed |
| WO-2023121447-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | SAPREME TECHNOLOGIES B.V. (NL) | 2023-06-29 | — | — | WO | disclosed |
| EP-4171646-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | Sapreme Technologies B.V. (NL) | 2023-05-03 | — | — | EP | disclosed |
| EP-4171647-A2 | COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE | Sapreme Technologies B.V. (NL) | 2023-05-03 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250295800-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | CYP46A1, HCCS, DHCR7 | FLT1 2324/4885ROR1 1136/4885GRB2 2354/4885 |
| US-20230248844-A1 | COMBINATION COMPRISING AN ADC OR AN AOC COMPRISING A VHH, AND A SAPONIN OR A LIGAND-SAPONIN CONJUGATE | HCCS, HAVCR2, HMBS | FLT1 1612/4885ROR1 1386/4885GRB2 1600/4885 |
| US-20230302140-A1 | CONJUGATE OF A SINGLE DOMAIN ANTIBODY, A SAPONIN AND AN EFFECTOR MOLECULE, PHARMACEUTICAL COMPOSITION COMPRISING THE SAME, THERAPEUTIC USE OF SAID PHARMACEUTICAL COMPOSITION | CYP46A1, HCCS, DHCR7 | FLT1 2324/4885ROR1 1136/4885GRB2 2354/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.