Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY5R | Q15761 | 1/20 | 0.57 |
| ▸ | BCHE | P06276 | 2/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.52 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9841040 | 0.83 | KDM4E (0.58) | NPY5RLMNASLC6A2CYP2C19SLC6A3 | |
| SCHEMBL2636610 | 0.83 | KDM4E (0.58) | NPY5RLMNASLC6A2CYP2C19SLC6A3 | |
| SCHEMBL2636608 | 0.83 | KDM4E (0.58) | NPY5RLMNASLC6A2CYP2C19SLC6A3 | |
| SCHEMBL11606393 | 0.82 | LMNA (0.66) | BCHEALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL11606605 | 0.80 | LMNA (0.63) | NPY5RBCHEPTGS1PTGS2L3MBTL1 | |
| SCHEMBL21360221 | 0.80 | LMNA (0.58) | NPY5RALOX5PTGS1PTGS2L3MBTL1 | |
| SCHEMBL1497960 | 0.79 | LMNA (0.61) | ALOX5PTGS1PTGS2L3MBTL1LMNA | |
| SCHEMBL24330472 | 0.77 | KDM4E (0.44) | LMNAMEN1KMT2ANPSR1 | |
| SCHEMBL5884767 | 0.77 | LTA4H (0.58) | NPY5RALOX5L3MBTL1LMNA | |
| SCHEMBL8440300 | 0.76 | BCHE (0.58) | BCHEALOX5PTGS1PTGS2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100081845-A1 | Process for Production of Optically Active Benzylamine Derivatives | ALPS PHARMACEUTICAL INC. CO., LTD. (JP) | 2010-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100081845-A1 | Process for Production of Optically Active Benzylamine Derivatives | RAB27A, HTR7, ALKBH1 | NPY5R 2279/4885BCHE 430/4885ALOX5 1571/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.