SCHEMBL6428557

SCHEMBL6428557

CCc1cc(Br)ccc1O.Cc1cc(Br)ccc1O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 1/20 0.48
POLB P06746 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
ESR1 P03372 8/20 0.46
ESR2 Q92731 8/20 0.46
HPGD P15428 2/20 0.45
HTT P42858 1/20 0.45
AR P10275 4/20 0.44
TSHR P16473 1/20 0.44
GFER P55789 1/20 0.44
BACE1 P56817 1/20 0.43
ALOX15 P16050 2/20 0.42
TP53 P04637 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
CYP1A2 P05177 2/20 0.41
CYP2C9 P11712 2/20 0.41
CYP3A4 P08684 1/20 0.41
PKM P14618 1/20 0.41
HIF1A Q16665 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82273 0.90 ALDH1A1 (0.54) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL30396162 0.90 ALDH1A1 (0.54) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
SCHEMBL49677 0.84
Methylhydroquinone SCHEMBL7772690 0.77 ESR1 (0.50) ESR1ESR2ARBACE1TP53
SCHEMBL7674042 0.76 ALOX15 (0.48) ALDH1A1KDM4EPOLBESR1ESR2
SCHEMBL30169578 0.76 PYCR1 (0.49) ALDH1A1SMN1; SMN2HPGDTSHRALOX15
SCHEMBL8365116 0.76 SMN1; SMN2 (0.41) ALDH1A1KDM4EPOLBSMN1; SMN2HPGD
SCHEMBL12164465 0.76 PYCR1 (0.49) ALDH1A1SMN1; SMN2HPGDTSHRALOX15
SCHEMBL574298 0.75 ALOX5 (0.50) ALDH1A1KDM4EPOLBSMN1; SMN2ESR1
Propene SCHEMBL4958342 0.75 ALOX15 (0.46) ALDH1A1KDM4ESMN1; SMN2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050233930-A1 Disinfectant cleaning compositions RECKITT BENCKISER INC. (US) 2005-10-20 US disclosed