Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 3/20 | 0.36 |
| ▸ | JAK1 | P23458 | 4/20 | 0.35 |
| ▸ | JAK2 | O60674 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | TYK2 | P29597 | 1/20 | 0.35 |
| ▸ | JAK3 | P52333 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.33 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
| ▸ | CKS1B | P61024 | 1/20 | 0.33 |
| ▸ | SKP1 | P63208 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25523570 | 0.87 | BTK (0.44) | BTKKMT2AL3MBTL1METJAK1 | |
| SCHEMBL25517566 | 0.82 | KMT2A (0.49) | BTKKMT2AL3MBTL1JAK1JAK2 | |
| SCHEMBL25523600 | 0.82 | KMT2A (0.41) | BTKKMT2AL3MBTL1METJAK1 | |
| SCHEMBL25529477 | 0.81 | MET (0.39) | BTKKMT2AL3MBTL1METMAPK13 | |
| SCHEMBL25524581 | 0.81 | MET (0.43) | BTKKMT2AL3MBTL1METJAK1 | |
| SCHEMBL30397426 | 0.81 | USP30 (0.41) | BTKKMT2AL3MBTL1METJAK1 | |
| SCHEMBL25525729 | 0.80 | BTK (0.43) | BTKKMT2AL3MBTL1CA1CA2 | |
| SCHEMBL25529454 | 0.80 | BTK (0.40) | BTKKMT2AL3MBTL1METMAPK13 | |
| SCHEMBL25540956 | 0.79 | BTK (0.42) | BTKKMT2AL3MBTL1METMAP4K4 | |
| SCHEMBL25533067 | 0.79 | BTK (0.44) | BTKKMT2AL3MBTL1JAK1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023091726-A1 | INHIBITORS OF CYCLIN‑DEPENDENT KINASE 12 (CDK12) | SYROS PHARMACEUTICALS, INC. (US) | 2023-05-25 | — | — | WO | disclosed |