Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | MGAM | O43451 | 2/20 | 0.49 |
| ▸ | AMY1A | P0DUB6 | 2/20 | 0.49 |
| ▸ | SI | P14410 | 2/20 | 0.49 |
| ▸ | MGAM2 | Q2M2H8 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21304645 | 0.76 | APAF1 (0.75) | APAF1POLBALDH1A1EGLN3RAB9A | |
| SCHEMBL5828539 | 0.75 | APAF1 (0.69) | APAF1POLBALDH1A1EGLN3RAB9A | |
| SCHEMBL27349798 | 0.75 | APAF1 (0.61) | APAF1POLBALDH1A1EGLN3RAB9A | |
| SCHEMBL26698323 | 0.75 | EGLN3 (0.56) | APAF1POLBEGLN3RAB9AGAA | |
| SCHEMBL23774830 | 0.74 | APAF1 (0.76) | APAF1POLBALDH1A1EGLN3RAB9A | |
| SCHEMBL5828228 | 0.73 | APAF1 (0.58) | APAF1POLBALDH1A1EGLN3RAB9A | |
| SCHEMBL4307811 | 0.72 | ADRB1 (0.44) | — | |
| SCHEMBL9772257 | 0.71 | APAF1 (0.59) | APAF1POLBALDH1A1EGLN3RAB9A | |
| SCHEMBL2070662 | 0.71 | GAA (0.67) | EGLN3RAB9AGAAMGAMAMY1A | |
| SCHEMBL4311442 | 0.71 | ADRB1 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111386118-B | Combination pharmaceutical agents as RSV inhibitors | 英安塔制药有限公司 | 2023-05-09 | — | — | CN | disclosed |