Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.69 |
| ▸ | POLB | P06746 | 1/20 | 0.69 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.57 |
| ▸ | GAA | P10253 | 7/20 | 0.56 |
| ▸ | MGAM | O43451 | 6/20 | 0.56 |
| ▸ | AMY1A | P0DUB6 | 6/20 | 0.56 |
| ▸ | SI | P14410 | 6/20 | 0.56 |
| ▸ | MGAM2 | Q2M2H8 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | SLC9A1 | P19634 | 2/20 | 0.51 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27349798 | 0.88 | APAF1 (0.61) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL21304645 | 0.86 | APAF1 (0.75) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL5828228 | 0.85 | APAF1 (0.58) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL10142232 | 0.83 | APAF1 (0.56) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL9772257 | 0.81 | APAF1 (0.59) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL240665 | 0.79 | APAF1 (0.66) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL29393597 | 0.79 | APAF1 (0.66) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL23774830 | 0.78 | APAF1 (0.76) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL972935 | 0.77 | APAF1 (0.62) | APAF1POLBEGLN3GAAMGAM | |
| SCHEMBL13729890 | 0.76 | APAF1 (0.78) | APAF1POLBEGLN3GAAMGAM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | claimed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | claimed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | claimed |
| US-7015331-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2006-03-21 | — | — | US | disclosed |
| US-20050222426-A1 | Non-proteinogenic L-amino acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2005-10-06 | — | — | US | disclosed |
| US-6939967-B2 | Non-proteinogenic L-amino acids | Consortium für elektrochemische Industrie GmbH (DE) | 2005-09-06 | — | — | US | disclosed |
| US-20040197879-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2004-10-07 | — | — | US | disclosed |
| US-6756216-B2 | BATCH PROCESSING USING NUCLEOPHILIC COMPOUND | Consortium für elektrochemische Industrie GmbH (DE) | 2004-06-29 | — | — | US | disclosed |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH | 2002-04-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050222426-A1 | Non-proteinogenic L-amino acids | BCAT2, BCAT1, CBS | APAF1 1306/4885POLB 2972/4885EGLN3 3686/4885 |
| US-20020039767-A1 | Process for producing non-proteinogenic L-amino acids by fermentation | CBS, BCAT2, BCAT1 | APAF1 1011/4885POLB 2545/4885EGLN3 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.