Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.51 |
| ▸ | PDCD1 | Q15116 | 4/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.49 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.47 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.47 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.47 |
| ▸ | CTSD | P07339 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.46 |
| ▸ | HNF4A | P41235 | 1/20 | 0.46 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28254835 | 1.00 | SUCNR1 (0.51) | SUCNR1PDCD1CD274L3MBTL1MAPT | |
| SCHEMBL29256186 | 0.85 | HDAC7 (0.59) | SUCNR1PDCD1CD274L3MBTL1GAA | |
| SCHEMBL6659064 | 0.84 | MKNK1 (0.49) | SUCNR1PDCD1CD274L3MBTL1MAPT | |
| SCHEMBL1826396 | 0.84 | CHRNB2 (0.65) | MAPTGAAGFERBCAT2CHRNB2 | |
| SCHEMBL30345390 | 0.84 | CHRNB2 (0.65) | MAPTGAAGFERBCAT2CHRNB2 | |
| SCHEMBL28112960 | 0.83 | MYC (0.49) | L3MBTL1CTSDRAB9AP2RX7MYC | |
| SCHEMBL7677836 | 0.83 | HNF4A (0.68) | L3MBTL1MAPTGAAGFERBCAT2 | |
| SCHEMBL436284 | 0.83 | KEAP1 (0.57) | SUCNR1PDCD1CD274L3MBTL1CHRNB2 | |
| Biphenyl SCHEMBL27596494 | 0.82 | CHRNB2 (0.62) | GAABCAT2CHRNB2CHRNB4CHRNA3 | |
| SCHEMBL28014189 | 0.82 | L3MBTL1 (0.43) | SUCNR1PDCD1CD274L3MBTL1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116041277-B | Phenyl and biphenyl substituted five-membered heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-11-01 | — | — | CN | disclosed |
| CN-115974807-B | 2-Phenyl-5-biphenyl-1, 3, 4-oxadiazole compound, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2024-05-31 | — | — | CN | disclosed |
| CN-116041277-A | Phenyl and biphenyl substituted five-membered heterocyclic compound, preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-05-02 | — | — | CN | disclosed |
| CN-115974807-A | 2-phenyl-5-biphenyl-1,3,4-oxadiazole compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-04-18 | — | — | CN | disclosed |