Adenosine Triphosphate

Adenosine Triphosphate

SCHEMBL3040412

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)([O-])OP(=O)(O)OP(=O)([O-])O)[C@@H](O)[C@H]1O.[K+].[K+]

nearest known ligand 0.78

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Known targets — ChEMBL curated mechanism

AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA

The experimentally established mechanism targets of Adenosine Triphosphate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
P2RY1 P47900 10/20 0.78
P2RY2 P41231 3/20 0.78
SRC P12931 2/20 0.78
SMN1; SMN2 Q16637 2/20 0.78
P2RX1 P51575 2/20 0.78
P2RX3 P56373 2/20 0.78
ALDH1A1 P00352 2/20 0.78
P2RX4 Q99571 1/20 0.78
P2RX2 Q9UBL9 1/20 0.78
TRPM2 O94759 2/20 0.75
P2RY11 Q96G91 2/20 0.75
TAS1R3 Q7RTX0 2/20 0.75
TAS1R1 Q7RTX1 2/20 0.75
DNPH1 O43598 1/20 0.75
PRKAB2 O43741 1/20 0.75
LDHA P00338 1/20 0.75
ADRB2 P07550 1/20 0.75
FBP1 P09467 1/20 0.75
ADORA1 P30542 1/20 0.75
PRKAG1 P54619 1/20 0.75

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adenosine Triphosphate SCHEMBL28357 0.98 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Triphosphate SCHEMBL3840392 0.97 P2RY1 (0.77) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Triphosphate SCHEMBL3498802 0.97 P2RY1 (0.77) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL28284912 0.96 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Triphosphate SCHEMBL2960692 0.95 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL4406433 0.95 P2RY1 (0.87) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL29444634 0.95 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL4734035 0.95 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL29723933 0.95 P2RY1 (0.78) P2RY1P2RY2SRCSMN1; SMN2P2RX1
Adenosine Diphosphate SCHEMBL11579601 0.94 P2RY1 (0.76) P2RY1P2RY2SRCSMN1; SMN2P2RX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116942918-A Self-solidifying composite bone implant based on human body essential amino acid and preparation method thereof 中鼎凯瑞科技成都有限公司 2023-10-27 CN claimed
CN-116606837-B Complex enzyme liquid for electrochemical detection of triglyceride, detection test paper and sensor 南京晶捷生物科技有限公司 2023-10-20 CN claimed
US-6255291-B1 MIXTURE OF ALANINE, ADENOSINE COMPOUND, RIBOSE COMPOUND, ASCORBIC ACID AND NICOTINIC ACID PEREGRINE PHARMACEUTICALS, INC. 2001-07-03 US claimed
CN-116942918-A Self-solidifying composite bone implant based on human body essential amino acid and preparation method thereof 中鼎凯瑞科技成都有限公司 2023-10-27 CN disclosed
US-20100222293-A1 MODULATION OF SPERM MOTILITY DUSKA SCIENTIFIC CO. 2010-09-02 US disclosed
US-6255291-B1 MIXTURE OF ALANINE, ADENOSINE COMPOUND, RIBOSE COMPOUND, ASCORBIC ACID AND NICOTINIC ACID PEREGRINE PHARMACEUTICALS, INC. 2001-07-03 US disclosed
EP-0967984-A1 COMPOSITION AND METHOD FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS RESULTING IN CHRONIC CONDITIONS Peregrine Pharmaceutical, Inc. (US) 2000-01-05 EP disclosed
WO-1998046206-A1 SKIN CREAM COMPOSITION PEREGRINE PHARMACEUTICAL, INC. (US) 1998-10-22 WO disclosed
WO-1998039013-A1 COMPOSITION AND METHOD FOR TREATING CANCER AND IMMUNOLOGICAL DISORDERS RESULTING IN CHRONIC CONDITIONS PEREGRINE PHARMACEUTICAL, INC. (US) 1998-09-11 WO disclosed