Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MERTK | Q12866 | 12/20 | 0.45 |
| ▸ | AXL | P30530 | 3/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 2/20 | 0.45 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.40 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | RET | P07949 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | KDR | P35968 | 1/20 | 0.35 |
| ▸ | FLT3 | P36888 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30405974 | 0.86 | TBXAS1 (0.41) | MERTKAXLTYRO3TBXAS1GRM5 | |
| SCHEMBL14699238 | 0.79 | TBXAS1 (0.44) | MERTKAXLTYRO3TBXAS1GRM5 | |
| SCHEMBL2237429 | 0.76 | PIK3CG (0.41) | MERTKAXLTYRO3TBXAS1DGAT1 | |
| SCHEMBL29172496 | 0.75 | TBXAS1 (0.40) | MERTKAXLTYRO3TBXAS1GRM5 | |
| SCHEMBL29930755 | 0.74 | L3MBTL1 (0.40) | MERTKTBXAS1GRM5 | |
| SCHEMBL5518448 | 0.74 | TBXAS1 (0.41) | TYRO3TBXAS1DGAT1MAPTAURKA | |
| SCHEMBL14699237 | 0.73 | CYP2A6 (0.37) | DGAT1MAPTCYP2A6CYP3A4CYP2D6 | |
| SCHEMBL29806073 | 0.73 | CYP2C19 (0.40) | DGAT1MAPTCYP2A6CYP3A4CYP2D6 | |
| SCHEMBL2608752 | 0.71 | ALDH1A1 (0.40) | TBXAS1DGAT1CYP2A6CYP3A4CYP2D6 | |
| SCHEMBL14713862 | 0.71 | PIM1 (0.46) | DGAT1MAPTCYP2A6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116171280-A | Casein kinase 1 delta modulators | 詹森药业有限公司 | 2023-05-26 | — | — | CN | disclosed |