Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | NOS3 | P29474 | 1/20 | 0.31 |
| ▸ | NOS1 | P29475 | 1/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL744179 | 1.00 | SLC6A4 (0.34) | SLC6A4SLC6A3C5AR1CHRNB2CHRNA4 | |
| SCHEMBL27672544 | 0.82 | HTR1A (0.42) | SLC6A4SLC6A3CHRNB2CHRNA4PDE10A | |
| SCHEMBL13646233 | 0.80 | SYK (0.36) | CHRNB2CHRNA4HRH3ALDH1A1 | |
| SCHEMBL8534738 | 0.79 | SLC6A4 (0.44) | SLC6A4SLC6A3C5AR1HRH3NOS3 | |
| SCHEMBL745497 | 0.78 | CHRNB2 (0.34) | CHRNB2CHRNA4HRH3 | |
| SCHEMBL25198368 | 0.78 | DHFR (0.36) | C5AR1CHRNB2CHRNA4PDE10AALDH1A1 | |
| SCHEMBL15180526 | 0.77 | HRH3 (0.42) | PDE10AHRH3NOS3NOS2ALDH1A1 | |
| SCHEMBL6267340 | 0.76 | PDE10A (0.31) | PDE10A | |
| SCHEMBL25188918 | 0.75 | ALOX5 (0.34) | ALDH1A1 | |
| SCHEMBL745011 | 0.75 | SMN1; SMN2 (0.35) | PDE10AMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023081666-A1 | COMPOUNDS AS CCR2 MODULATORS | ARIA PHARMACEUTICALS, INC. (US) | 2023-05-11 | — | — | WO | disclosed |