Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 8/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.46 |
| ▸ | CCKBR | P32239 | 1/20 | 0.45 |
| ▸ | PTPN2 | P17706 | 2/20 | 0.43 |
| ▸ | PTPRA | P18433 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP7 | P09237 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP12 | P39900 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.42 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13744704 | 0.89 | ITGB3 (0.48) | ITGB3ITGA2BPTPN1MMP2MMP7 | |
| SCHEMBL7299599 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL9742835 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL13716830 | 0.89 | L3MBTL1 (0.56) | ITGB3ITGA2BPTPN1MMP2MMP7 | |
| Trifluoroacetic Acid SCHEMBL3040708 | 0.87 | ITGB3 (0.50) | ITGB3ITGA2BPTPN1PTPN2PTPRA | |
| SCHEMBL13716640 | 0.87 | ITGB3 (0.64) | ITGB3ITGA2B | |
| SCHEMBL7303040 | 0.83 | ITGB3 (0.55) | ITGB3ITGA2BPTPN1 | |
| SCHEMBL13716827 | 0.82 | CCKBR (0.45) | ITGB3ITGA2BPTPN1CCKBRMMP2 | |
| SCHEMBL7296817 | 0.82 | MAPT (0.44) | ITGB3ITGA2BCCKBRMMP9MMP1 | |
| SCHEMBL7298590 | 0.82 | PRSS1 (0.47) | ITGB3ITGA2BPTPN1PTPN2PTPRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7576071-B2 | Antithrombotic compound | SANOFI-AVENTIS (FR) | 2009-08-18 | — | — | US | disclosed |
| US-20070293442-A1 | ANTITHROMBOTIC COMPOUND | SANOFI-AVENTIS (FR) | 2007-12-20 | — | — | US | disclosed |
| US-20070293442-A1 | ANTITHROMBOTIC COMPOUND | SANOFI-AVENTIS (FR) | 2007-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070293442-A1 | ANTITHROMBOTIC COMPOUND | F13B, SERPINC1, SELP | ITGB3 66/4885ITGA2B 13/4885PTPN1 2299/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.