Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 16/20 | 0.50 |
| ▸ | TMPRSS15 | P98073 | 16/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPRA | P18433 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.46 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9582910 | 0.92 | TMPRSS15 (0.49) | PRSS1TMPRSS15ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL9222086 | 0.90 | NPY4R (0.48) | PRSS1TMPRSS15PTPN1PTPN2PTPRA | |
| Trifluoroacetic Acid SCHEMBL3040708 | 0.88 | ITGB3 (0.50) | PRSS1TMPRSS15PTPN1PTPN2PTPRA | |
| SCHEMBL7298590 | 0.87 | PRSS1 (0.47) | PRSS1TMPRSS15PTPN1PTPN2PTPRA | |
| SCHEMBL9742835 | 0.85 | ITGB3 (0.51) | PRSS1TMPRSS15PTPN1PTPN2PTPRA | |
| SCHEMBL7299599 | 0.85 | ITGB3 (0.51) | PRSS1TMPRSS15PTPN1PTPN2PTPRA | |
| Trifluoroacetic Acid SCHEMBL9582897 | 0.81 | ACE (0.51) | PRSS1TMPRSS15ITGB3ITGA2B | |
| SCHEMBL7332549 | 0.80 | FOLH1 (0.49) | PRSS1TMPRSS15ITGB3ITGA2B | |
| SCHEMBL7303040 | 0.80 | ITGB3 (0.55) | PTPN1ITGB3ITGA2B | |
| Trifluoroacetic Acid SCHEMBL7308419 | 0.79 | ITGB3 (0.46) | ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | claimed |
| EP-0445796-B1 | Derivatives of acetic acid containing peptide bonds | HOFFMANN LA ROCHE (CH) | 1998-06-17 | — | — | EP | disclosed |
| US-5430024-A | Peptides bearing N-terminal amidino moieties and their use as inhibitors of platelet aggregation | HOFFMANN-LA ROCHE INC. (US) | 1995-07-04 | — | — | US | disclosed |
| EP-0445796-A2 | Derivatives of acetic acid | F. HOFFMANN-LA ROCHE AG (CH) | 1991-09-11 | — | — | EP | disclosed |