Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.92 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.92 |
| ▸ | ESR1 | P03372 | 4/20 | 0.63 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.33 |
| ▸ | CA1 | P00915 | 2/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224339 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL28032492 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL3187741 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL4657174 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL3222418 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL521959 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL7538351 | 1.00 | TDP1 (0.92) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL11149268 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL11146028 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E | |
| SCHEMBL11147789 | 0.96 | TDP1 (0.86) | TDP1CYP3A4ESR1ESR2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230414655-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VENOM RELATED POISONING | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA | 2023-12-28 | — | — | US | claimed |
| WO-2022133109-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VENOM RELATED POISONING | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2022-06-23 | — | — | WO | claimed |
| US-6909019-B1 | Process for preparing aldehydes | EASTMAN CHEMICAL COMPANY (US) | 2005-06-21 | — | — | US | claimed |
| EP-0516982-B1 | Process for producing a heterocyclic tertiary amine | NISSAN CHEMICAL IND LTD (JP) | 1998-09-16 | — | — | EP | claimed |
| US-5283341-A | Catalytic alkylation | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1994-02-01 | — | — | US | claimed |
| EP-0516982-A1 | Process for producing a heterocyclic tertiary amine | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 1992-12-09 | — | — | EP | claimed |
| EP-0403706-A2 | Process for preparing amino-propyl silanes | Tonen Corporation (JP) | 1990-12-27 | — | — | EP | claimed |
| US-4927953-A | Process for preparing aminopropyl silanes | TONEN CORPORATION (JP) | 1990-05-22 | — | — | US | claimed |
| JP-9291065-A | — | — | None | — | — | JP | disclosed |
| JP-63216857-A | — | — | None | — | — | JP | disclosed |
| JP-63216844-A | — | — | None | — | — | JP | disclosed |
| US-20250075079-A1 | POLYMERIC FLUOROPHORES, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME | UNIV NORTH CAROLINA STATE (US) | 2025-03-06 | — | — | US | disclosed |
| US-12139617-B2 | Polymeric fluorophores, compositions comprising the same, and methods of preparing and using the same | NORTH CAROLINA STATE UNIVERSITY (US) | 2024-11-12 | — | — | US | disclosed |
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2024-06-18 | — | — | US | disclosed |
| US-4629472-A | DISPERSION OF PRECIOUS METAL CATALYSTS WITHIN FUELS | FUEL TECH, INC. (US) | 1986-12-16 | — | — | US | disclosed |
| US-4548763-A | Preparation of vinylphosphonate diesters | ALLIED CORPORATION (US) | 1985-10-22 | — | — | US | disclosed |
| US-4465847-A | Method for the production of butyrolactones | RAMOT UNIVERSITY AUTHORITY FOR APPLIED RESEARCH AND INDUSTRY DEVELOPMENT LTD. (IL) | 1984-08-14 | — | — | US | disclosed |
| US-4317946-A | IN THE PRESENCE OF A RUTHENIUM CATALYST | THE HALCON SD GROUP, INC. (US) | 1982-03-02 | — | — | US | disclosed |
| US-4190595-A | REACTION WITH AN ALKALI OR ALKALINE EARTH METAL ALKYLAMIDE | ALLIED CHEMICAL CORPORATION (US) | 1980-02-26 | — | — | US | disclosed |
| US-4117016-A | PROCESS FOR STRUCTURAL MODIFICATION OF UNSATURATED ALCOHOLS | PHILLIPS PETROLEUM COMPANY (US) | 1978-09-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12012426-B2 | Tetradentate diaminodiphosphine ligand and transition metal complex, and method for manufacturing same and application for same | ADH4, ADH5, PF4 | TDP1 2933/4885CYP3A4 75/4885ESR1 4569/4885 |
| US-20250075079-A1 | POLYMERIC FLUOROPHORES, COMPOSITIONS COMPRISING THE SAME, AND METHODS OF PREPARING AND USING THE SAME | CLTB, PAICS, HLCS | TDP1 2927/4885CYP3A4 2891/4885ESR1 2443/4885 |
| US-12139617-B2 | Polymeric fluorophores, compositions comprising the same, and methods of preparing and using the same | CLTB, PAICS, HLCS | TDP1 2927/4885CYP3A4 2891/4885ESR1 2443/4885 |
| US-20230414655-A1 | COMPOSITIONS AND METHODS FOR TREATING AND PREVENTING VENOM RELATED POISONING | PLA2G12A, PLA2G12B, PLA2G1B | TDP1 760/4885CYP3A4 960/4885ESR1 3801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.