Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BMP1 | P13497 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.33 |
| ▸ | KAT6A | Q92794 | 2/20 | 0.33 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416910 | 0.79 | KMT2A (0.41) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL30416463 | 0.78 | STING1 (0.44) | KMT2A | |
| SCHEMBL26673391 | 0.69 | SLC6A3 (0.45) | ALDH1A1GAAKMT2ATSHRMEN1 | |
| SCHEMBL24710640 | 0.67 | RAB9A (0.42) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL23360861 | 0.67 | GSK3B (0.56) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL23384735 | 0.67 | NPC1 (0.42) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| Hydrochloric Acid SCHEMBL28944721 | 0.66 | NPC1 (0.41) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL17462467 | 0.65 | CA1 (0.52) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL31521762 | 0.65 | CA1 (0.52) | ALDH1A1GAAKMT2AMEN1NPC1 | |
| SCHEMBL30416829 | 0.65 | ALDH1A1 (0.55) | ALDH1A1KMT2ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |