Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 13/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30416910 | 0.87 | KMT2A (0.41) | KMT2A | |
| SCHEMBL26673329 | 0.86 | CES2 (0.43) | STING1L3MBTL1 | |
| SCHEMBL11203155 | 0.78 | CES2 (0.56) | KMT2AL3MBTL1 | |
| SCHEMBL30416404 | 0.78 | BMP1 (0.36) | KMT2A | |
| SCHEMBL30416829 | 0.77 | ALDH1A1 (0.55) | STING1KMT2A | |
| SCHEMBL23384735 | 0.76 | NPC1 (0.42) | KMT2A | |
| SCHEMBL23360861 | 0.76 | GSK3B (0.56) | KMT2A | |
| SCHEMBL24710640 | 0.76 | RAB9A (0.42) | KMT2A | |
| SCHEMBL1376745 | 0.76 | L3MBTL1 (0.58) | L3MBTL1 | |
| SCHEMBL573257 | 0.76 | HCAR1 (0.53) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111971277-B | Benzothiophenes and related compounds as STING agonists | 默沙东有限责任公司 | 2023-06-06 | — | — | CN | disclosed |