Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.63 |
| ▸ | LMNA | P02545 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.63 |
| ▸ | HPGD | P15428 | 1/20 | 0.63 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.52 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.51 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.51 |
| ▸ | PARP1 | P09874 | 5/20 | 0.49 |
| ▸ | SMO | Q99835 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19951504 | 1.00 | TSHR (0.63) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL19951493 | 0.88 | LMNA (0.51) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL30418223 | 0.88 | LMNA (0.51) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL13721430 | 0.84 | PARP1 (0.53) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL13720770 | 0.84 | HTR3A (0.53) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL831675 | 0.83 | ENPP1 (0.53) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL29688141 | 0.83 | ENPP1 (0.53) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL13720391 | 0.82 | ALDH1A1 (0.60) | LMNAALDH1A1HPGDENPP1ROCK2 | |
| SCHEMBL13720327 | 0.81 | ENPP1 (0.55) | TSHRLMNAALDH1A1HPGDENPP1 | |
| SCHEMBL5160196 | 0.80 | LMNA (0.57) | TSHRLMNAALDH1A1HPGDPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4419094-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | Edison Oncology (US) | 2024-08-28 | — | — | EP | disclosed |
| WO-2023069727-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF HYPERPROLIFERATIVE, INFLAMMATORY, AND IMMUNOLOGICAL DISEASES, AND INFECTIONS | EDISON ONCOLOGY (US) | 2023-04-27 | — | — | WO | disclosed |